Evidence map›Paper›PMID 34238746›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[Design, screening and antibacterial activity evaluation of the novel antibacterial peptide KR-1].

J He, D Liang, Y Liang, S Zuo, W Zhao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J HeDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
D LiangDepartment of Stomatology, Affiliated Zhongshan Hospital of Sun Yat-sen University, Zhongshan 528400, China.
Y LiangDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
S ZuoDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
W ZhaoDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nanfang Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo design novel antimicrobial peptides with high activity and low toxicity and evaluate their effect against

objectiveWe synthesized two antimicrobial peptides (KR-1 and KR-2) using Dhvar4 (a histatins5 mimic) as the template. The antimicrobial peptides with high activity and low toxicity were screened using minimal inhibitory concentration (MIC) test, hemolysis test, and CCK-8 assay.

objectiveThe MIC of KR-1 and KR-2 for

objectiveThe antimicrobial peptide KR-1 has a stronger antibacterial activity and a low toxicity with a good inhibitory effect against

Indexed as

Anti-Infective AgentsDental CariesAnimalsAnti-Bacterial AgentsBiofilmsMicrobial Sensitivity TestsPeptidesRabbitsStreptococcus mutansAnti-Bacterial AgentsAnti-Infective AgentsPeptidesantibacterial peptidesbiofilmStreptococcus mutans

Identifiers

PMID34238746
PMCPMC8267989
OpenAlexW3181111492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.