Evidence map›Paper›PMID 34238538›Full record

SynthesisInjury2021

Metrics of shock in pediatric trauma patients: A systematic search and review.

Emily C Alberto, Elise McKenna, Michael J Amberson, Jun Tashiro, Katie Donnelly, Arunachalam A Thenappan, Peyton E Tempel, Adesh S Ranganna, Susan Keller, Ivan Marsic and 3 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Injury, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Emily C AlbertoDivision of Trauma and Burn Surgery, Children's National Hospital, Washington D.C., United States.
Elise McKennaDivision of Trauma and Burn Surgery, Children's National Hospital, Washington D.C., United States.
Michael J AmbersonDepartment of Pediatrics, Children's National Hospital, Washington D.C., United States.
Jun TashiroDivision of Trauma and Burn Surgery, Children's National Hospital, Washington D.C., United States.
Katie DonnellyDivision of Emergency Medicine, Children's National Hospital, Washington D.C., United States.
Arunachalam A ThenappanDivision of Trauma and Burn Surgery, Children's National Hospital, Washington D.C., United States.
Peyton E TempelDivision of Trauma and Burn Surgery, Children's National Hospital, Washington D.C., United States.
Adesh S RangannaDivision of Trauma and Burn Surgery, Children's National Hospital, Washington D.C., United States.
Susan KellerDepartment of Nursing Science Professional Practice and Quality, Children's National Hospital, Washington D.C., United States.
Ivan MarsicDepartment of Electrical and Computer Engineering, Rutgers University, Piscataway, NJ, United States.
Aleksandra SarcevicCollege of Computing and Informatics, Drexel University, Philadelphia, PA, United States.
Karen J O'ConnellDivision of Emergency Medicine, Children's National Hospital, Washington D.C., United States.
Randall S BurdDivision of Trauma and Burn Surgery, Children's National Hospital, Washington D.C., United States. Electronic address: rburd@childrensnational.org.
Children's National · USDrexel University · USRutgers, The State University of New Jersey · US

Funding

Intention-aware Recommender System for Improving Trauma Resuscitation OutcomesR01LM011834 · NLM · CHILDREN'S RESEARCH INSTITUTE · PI BURD, RANDALL S., MARSIC, IVAN · 2014 to 2023
$4.7M
NLM NIH HHS R01 LM011834
6 · The paper itself

Abstract

introductionShock-index (SI) and systolic blood pressure (SBP) are metrics for identifying children and adults with hemodynamic instability following injury. The purpose of this systematic review was to assess the quality of these metrics as predictors of outcomes following pediatric injury. MATERIALS AND

methodsWe conducted a literature search in Pubmed, SCOPUS, and CINAHL to identify studies describing the association between shock metrics on the morbidity and mortality of injured children and adolescents. We used the data presented in the studies to calculate the sensitivity and specificity for each metric. This study was registered with Prospero, protocol CRD42020162971.

resultsFifteen articles met the inclusion criteria. seven studies evaluated SI or SIPA score, an age-corrected version of SI, as predictors of outcomes following pediatric trauma, with one study comparing SIPA score and SBP and one study comparing SI and SBP. The remaining eight studies evaluated SBP as the primary indicator of shock. The median sensitivity for predicting mortality and need for blood transfusion was highest for SI, followed by SIPA, and then SBP. The median specificity for predicting these outcomes was highest for SBP, followed by SIPA, and then SI.

conclusionsCommon conclusions were that high SIPA scores were more specific than SI and more sensitive than SBP. SIPA score had better discrimination for severely injured children compared to SI and SBP. An elevated SIPA was associated with a greater need for blood transfusion and higher in-hospital mortality. SIPA is specific enough to exclude most patients who do not require a blood transfusion.

Indexed as

ShockWounds and InjuriesAdolescentAdultBlood PressureChildHumansInjury Severity ScoreRetrospective StudiesHypotensionPediatricsResuscitationShock, TraumaticWounds and injuries

Identifiers

PMID34238538
PMCPMC8560576
OpenAlexW3173663969

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.