Evidence map›Paper›PMID 34238510›Full record

ArticleJournal de medecine vasculaire2021

Systematic screening for a proximal DVT in COVID-19 hospitalized patients: Results of a comparative study.

Y Fares, Y C Sinzogan-Eyoum, P Billoir, A Bogaert, G Armengol, K Alexandre, J Lammens, M Grall, H Levesque, Y Benhamou and 1 more

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal de medecine vasculaire, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Y FaresDepartment of internal medicine, Rouen university hospital, 76000 Rouen, France.
Y C Sinzogan-EyoumDepartment of internal medicine, Rouen university hospital, 76000 Rouen, France.
P BilloirDepartment of vascular haemostasis, Rouen university hospital, Normandie university, 76000 Rouen, France.
A BogaertDepartment of internal medicine, Rouen university hospital, 76000 Rouen, France.
G ArmengolUNIROUEN, Inserm U1096 EnVI, department of internal medicine, Rouen university hospital, Normandie university, 76000 Rouen, France.
K AlexandreDepartment of infectious diseases, Rouen university hospital, 76000 Rouen, France.
J LammensDepartment of internal medicine, Rouen university hospital, 76000 Rouen, France.
M GrallDepartment of internal medicine, Rouen university hospital, 76000 Rouen, France; Department of medical intensive care unit, Rouen university hospital, 76000 Rouen, France.
H LevesqueUNIROUEN, Inserm U1096 EnVI, department of internal medicine, Rouen university hospital, Normandie university, 76000 Rouen, France.
Y BenhamouUNIROUEN, Inserm U1096 EnVI, department of internal medicine, Rouen university hospital, Normandie university, 76000 Rouen, France.
S MirandaUNIROUEN, Inserm U1096 EnVI, department of internal medicine, Rouen university hospital, Normandie university, 76000 Rouen, France. Electronic address: Sebastien.miranda@chu-rouen.fr.
Université de Rouen Normandie · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe COVID-19 pandemic is associated with a high incidence of venous thromboembolism questioning the utility of a systematic screening for deep venous thrombosis (DVT) in hospitalised patients.

methodsIn this prospective bicentric controlled study, 4-point ultrasound using a pocket device was used to screen for DVT, in patients with SARS-CoV-2 infection and controls admitted for acute medical illness not related to COVID-19 hospitalised in general ward, in order to assess the utility of a routine screening and to estimate the prevalence of VTE among those patients.

resultsBetween April and May 2020, 135 patients were screened, 69 in the COVID+ group and 66 in the control one. There was no significant difference in the rate of proximal DVT between the two groups (2.2% vs. 1.5%; P=0.52), despite the high rate of PE diagnosed among COVID-19 infected patients (10.1% vs. 1.5%, P=0.063). No isolated DVT was detected, 37.5% of PE was associated with DVT. Mortality (7.2% vs. 1.5%) was not different (P=0.21) between COVID-19 patients and controls.

conclusionThe systematic screening for proximal DVT was not found to be relevant among COVID-19 patients hospitalized in general ward despite the increase of VTE among this population. Further studies are needed to confirm the hypothesis of a local pulmonary thrombosis which may lead to new therapeutic targets.

Indexed as

Diagnostic Screening ProgramsHospitalizationUltrasonographyAgedAged, 80 and overCase-Control StudiesCOVID-19FemaleFranceHumansIncidenceMaleMiddle AgedPredictive Value of TestsPrevalenceProspective StudiesCOVID-19Deep venous thrombosisPocket-sized ultrasound deviceScreening

Identifiers

PMID34238510
PMCPMC8118667
OpenAlexW3163134230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.