ArticleJournal of the American Heart Association2021
Regional Adiposity and Risk of Heart Failure and Mortality: The Jackson Heart Study.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Prognostic value of epicardial adipose tissue in heart failure: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Linking abnormal fat distribution with HFpEF and diastolic dysfunction: a systematic review, meta-analysis, and meta-regression of observational studies.Lipids in health and disease · 2024Pooled it
- Body Composition and Risk of Incident Heart Failure in 1 Million Adults: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.Journal of the American Heart Association · 2023Pooled it
- Exploring the impact of metabolic comorbidities on epicardial adipose tissue in heart failure with preserved ejection fraction.Cardiovascular diabetology · 2025Trial
- Impaired adipogenesis and lipid storage capacity in subcutaneous adipose tissue of patients with PMOS.JCI insight · 2026Article
- Role of systemic and epicardial adipose tissue in cardiometabolic disease.Nature reviews. Cardiology · 2026Review
- Greater amounts of visceral adipose and lean body mass increase heart failure risk in older women.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- The prognostic value of CT-measured body composition combined with radiomics in predicting the survival of patients with resectable colon cancer.La Radiologia medica · 2026Article
- Adipose tissue distribution in metabolic disease: depot-specific biology, clinical assessment, and therapeutic remodeling.Frontiers in endocrinology · 2026Review
- Article
- Epicardial Adipose Tissue (Pericoronary Adipose Tissue) in Cardiovascular Diseases.International journal of heart failure · 2025Article
- Skeletal muscle and subcutaneous fat quantity as prognostic indicators in cardiac amyloidosis.European journal of heart failure · 2025Article
- The causal relationships between body composition and heart failure: A two-sample mendelian randomization study.Scientific reports · 2025Article
- Prediction of abnormal bone mass with a pericoronary adipose tissue Attenuation model.BMC geriatrics · 2025Article
- Epicardial Fat in Heart Failure and Preserved Ejection Fraction: Novel Insights and Future Perspectives.Current heart failure reports · 2025Review
- Sex differences in the relationship between body composition and cardiac structure and function.European heart journal. Cardiovascular Imaging · 2025Article
- Associations between dynamic change of Chinese visceral adiposity index and hypertensive co-morbidities in the middle-aged and elderly population: a Chinese prospective cohort study.Frontiers in nutrition · 2025Article
- Increased epicardial adipose tissue is associated with left ventricular reverse remodeling in dilated cardiomyopathy.Cardiovascular diabetology · 2024Article
- Prognostic Value of Epicardial Adipose Tissue in Heart Failure With Mid-Range and Preserved Ejection Fraction: A Multicenter Study.Journal of the American Heart Association · 2024Article
- Association between Long-Term Exposure to Traffic-Related Air Pollution and Cardio-Metabolic Phenotypes: An MRI Data-Based Analysis.Environmental science & technology · 2024Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
Background Visceral adipose tissue (VAT) is associated with incident heart failure (HF) and HF with preserved ejection fraction, yet it is unknown how pericardial and abdominal adiposity affect HF and mortality risks in Black individuals. We examined the associations of pericardial adipose tissue (PAT), VAT, and subcutaneous adipose tissue (SAT) with incident HF hospitalization and all-cause mortality in a large community cohort of Black participants. Methods and Results Among the 2882 Jackson Heart Study Exam 2 participants without prevalent HF who underwent body computed tomography, we used Cox proportional hazards models to examine associations between computed tomography-derived regional adiposity and incident HF hospitalization and all-cause mortality. Fully adjusted models included demographics and cardiovascular disease risk factors. Median follow-up was 10.6 years among participants with available VAT (n=2844), SAT (n=2843), and PAT (n=1386). Fully adjusted hazard ratios (95% CIs) of distinct computed tomography-derived adiposity measures (PAT per 10 cm
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.