Evidence map›Paper›PMID 34238023›Full record

ArticleJournal of the American Heart Association2021

Treatment Inertia in Patients With Familial Hypercholesterolemia.

Anatoly Langer, G B John Mancini, Mary Tan, Shaun G Goodman, Vineeta Ahooja, Jean Grégoire, Peter J Lin, James A Stone, Lawrence A Leiter

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Treatment Inertia in Patients With Familial Hypercholesterolemia.Journal of the American Heart Association · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Anatoly LangerCanadian Heart Research Centre Toronto ON Canada.
G B John ManciniUniversity of British Columbia Vancouver Canada.
Mary TanCanadian Heart Research Centre Toronto ON Canada.
Shaun G GoodmanCanadian Heart Research Centre Toronto ON Canada.
Vineeta AhoojaCanadian Heart Research Centre Toronto ON Canada.
Jean GrégoireUniversité de MontréalInstitut de cardiologie de Montréal Montreal QC Canada.
Peter J LinCanadian Heart Research Centre Toronto ON Canada.
James A StoneCumming School of Medicine University of Calgary Calgary Canada.
Lawrence A LeiterLi Ka Shing Knowledge InstituteSt. Michael's HospitalUniversity of Toronto Toronto ON Canada.
Canadian Heart Research Centre · CASt. Michael's Hospital · CAMontreal Heart Institute · CAUniversity of British Columbia · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background We studied care gap in patients with familial hypercholesterolemia (FH) with respect to lipid-lowering therapy. Methods and Results We enrolled patients with cardiovascular disease (CVD) or FH and low-density lipoprotein-cholesterol >2.0 mmol/L despite maximally tolerated statin therapy. During follow-up physicians received online reminders of treatment recommendations of 2009 patients (median age, 63 years, 42% women), 52.4% had CVD only, 31.7% FH only, and 15.9% both CVD and FH. Patients with FH were younger and more likely to be women and non-White with significantly higher baseline low-density lipoprotein-cholesterol level (mmol/L) as compared with patients with CVD (FH 3.92±1.48 versus CVD 2.96±0.94,

Indexed as

AgedAnticholesteremic AgentsCardiovascular DiseasesCholesterol, LDLEzetimibeFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipoproteinemia Type IILogistic ModelsMaleMiddle AgedMultivariate AnalysisTreatment OutcomeAnticholesteremic AgentsCholesterol, LDLEzetimibeHydroxymethylglutaryl-CoA Reductase Inhibitorsfamilial hypercholesterolemialipid loweringtreatment inertia

Identifiers

PMID34238023
PMCPMC8483494
OpenAlexW3182438669

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.