Evidence map›Paper›PMID 34238021›Full record

ArticleCirculation research2021

Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19.

Duco Steven Koenis, Issa Beegun, Charlotte Camille Jouvene, Gabriel Amador Aguirre, Patricia Regina Souza, Maria Gonzalez-Nunez, Lucy Ly, Kimberly Pistorius, Hemant M Kocher, William Ricketts and 5 more

Open access · greenAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Enhanced Production of Lipid Mediators in Plasma and Activation of DNA Damage Pathways in PBMCs Are Correlated With the Severity of Ancestral SARS-CoV-2 Infection.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Identification of novel FRedox biology · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Duco Steven KoenisWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Issa Beegun *William Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Charlotte Camille Jouvene *William Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Gabriel Amador AguirreBarts Cancer Institute (G.A.A., H.M.K.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Patricia Regina SouzaWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Maria Gonzalez-NunezWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Lucy LyWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Kimberly PistoriusWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Hemant M KocherBarts Cancer Institute (G.A.A., H.M.K.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
William RickettsDepartment of Respiratory Medicine, Barts Health NHS Trust, London, United Kingdom (W.R., G.T., P.P.).
Gavin ThomasDepartment of Respiratory Medicine, Barts Health NHS Trust, London, United Kingdom (W.R., G.T., P.P.).
Mauro PerrettiWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Ghassan AlusiWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Paul PfefferWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Jesmond DalliWilliam Harvey Research Institute (D.S.K., I.B., C.C.J., P.R.S., M.G.N., L.L., K.P., M.P., G.A., P.P., J.D.), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
Queen Mary University of London · GBBarts Health NHS Trust · GB

Funding

European Research Council 677542Wellcome Trust 107613
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Cells, CulturedCOVID-19HumansInflammation MediatorsLeukocytes, MononuclearNeutrophilsPhagocytesInflammation Mediatorscovid-19homeostasisinflammation mediatorsmacrophagesmonocyteneutrophilsomega-3 fatty acidsphenotypeplasma

Identifiers

PMID34238021
PMCPMC8336787
OpenAlexW3178797008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.