Evidence map›Paper›PMID 34237276›Full record

ArticleNeuron2021

DRD3-dependent plasticity within the VP drives subcircuit activity critical for cocaine seeking.

Rianne R Campbell, Mary Kay Lobo

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rianne R CampbellDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Mary Kay LoboDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: mklobo@som.umaryland.edu.
University of Maryland, Baltimore · US

Funding

Cocaine-induced mitochondrial mechanisms and molecular mediators in reward circuitryR01DA038613 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LOBO, MARY KAY · 2014 to 2025
$4.9M
Ventral pallidum molecular mediators in cocaine addictionR01DA047843 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LOBO, MARY KAY · 2019 to 2023
$2.2M
NIDA NIH HHS R01 DA038613NIDA NIH HHS R01 DA047843
6 · The paper itself

Abstract

The ventral pallidum (VP) is a key hub within the reward system that mediates drug-seeking behaviors. However, molecular and cellular adaptations within the VP following drug use are not fully elucidated. In this issue of Neuron, Pribiag et al. (2021) demonstrate how cocaine induces circuit-specific changes within the VP via dopamine-receptor-D3-dependent processes to promote cocaine seeking.

Indexed as

Basal ForebrainCocaineDrug-Seeking BehaviorNeuronsRewardCocaine

Identifiers

PMID34237276
OpenAlexW3178106676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.