Evidence map›Paper›PMID 34236851›Full record

ArticleJournal of the American Society for Mass Spectrometry2021

From Preassociation to Chelation: A Survey of Cisplatin Interaction with Methionine at Molecular Level by IR Ion Spectroscopy and Computations.

Roberto Paciotti, Davide Corinti, Philippe Maitre, Cecilia Coletti, Nazzareno Re, Barbara Chiavarino, Maria Elisa Crestoni, Simonetta Fornarini

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Roberto PaciottiDipartimento di Farmacia, Università G. D'Annunzio Chieti-Pescara, Via dei Vestini 31, Chieti I-66100, Italy.
Davide CorintiDipartimento di Chimica e Tecnologie del Farmaco, Università di Roma "La Sapienza", I-00185 Roma, Italy.ORCID https://orcid.org/0000-0001-8064-3492
Philippe MaitreInstitut de Chimie Physique, Université Paris-Saclay, CNRS, F-91405 Orsay, France.ORCID https://orcid.org/0000-0003-2924-1054
Cecilia ColettiDipartimento di Farmacia, Università G. D'Annunzio Chieti-Pescara, Via dei Vestini 31, Chieti I-66100, Italy.ORCID https://orcid.org/0000-0002-3609-290X
Nazzareno ReDipartimento di Farmacia, Università G. D'Annunzio Chieti-Pescara, Via dei Vestini 31, Chieti I-66100, Italy.ORCID https://orcid.org/0000-0002-0957-4049
Barbara ChiavarinoDipartimento di Chimica e Tecnologie del Farmaco, Università di Roma "La Sapienza", I-00185 Roma, Italy.ORCID https://orcid.org/0000-0002-1585-7061
Maria Elisa CrestoniDipartimento di Chimica e Tecnologie del Farmaco, Università di Roma "La Sapienza", I-00185 Roma, Italy.ORCID https://orcid.org/0000-0002-0991-5034
Simonetta FornariniDipartimento di Chimica e Tecnologie del Farmaco, Università di Roma "La Sapienza", I-00185 Roma, Italy.ORCID https://orcid.org/0000-0002-6312-5738
Sapienza University of Rome · ITUniversity of Chieti-Pescara · ITCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methionine (Met) plays an important role in the metabolism of cisplatin anticancer drug. Yet, methionine platination in aqueous solution presents a highly complex pattern of interconnected paths and intermediates. This study reports on the reaction of methionine with the active aqua form of cisplatin,

Indexed as

AmmoniaAntineoplastic AgentsChelating AgentsCisplatinLigandsMethionineModels, ChemicalModels, MolecularMolecular ConformationPlatinumSolutionsSolventsSpectrometry, Mass, Electrospray IonizationSpectrophotometry, InfraredAmmoniaAntineoplastic AgentsChelating AgentsCisplatinLigandsMethioninePlatinumSolutionsSolvents

Identifiers

PMID34236851
PMCPMC8397306
OpenAlexW3180252267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.