Evidence map›Paper›PMID 34236778›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2021

The Heterogeneity of COPD Patients in a Community-Based Practice and the Inadequacy of the Global Initiative for Chronic Obstructive Lung Disease Criteria: A Real-World Experience.

Fortune O Alabi, Hadaya A Alkhateeb, Kayla M DeBarros, Pierina S Barletti Benel, Rachel L Sanchez-Martez, Mia L Zeper, Reema A Ismail, Fred Umeh, Nelson Medina-Villanueva

Abstract read
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  10. Prevalence of Chronic Obstructive Pulmonary Disease in an Urban Area. Changes in COPD Ten Years on.International journal of chronic obstructive pulmonary disease · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fortune O AlabiFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Hadaya A AlkhateebFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Kayla M DeBarrosFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Pierina S Barletti BenelFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Rachel L Sanchez-MartezFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Mia L ZeperFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Reema A IsmailFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Fred UmehFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.
Nelson Medina-VillanuevaFlorida Lung Asthma and Sleep Specialists, Kissimmee, Florida, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is a heterogeneous disease with differing clinical presentations, which range from an asymptomatic obstructive defect on spirometry to symptomatic normal spirometry. The current standard for diagnosis requires exposure history and the presence of an obstructive ventilatory defect (forced expiratory volume in 1 second [FEV

methodsWe retrospectively analyzed the charts of 2115 patients for eligibility. A total of 1224 patients with physician-diagnosed COPD were selected for this study. The average age was 68.4±11.5 years, with 51% being female. Of the 1224 patients, 18% did not have a history of smoking, 73% had bronchodilator testing, and a significant response of ≥12% was noted in 23% of the COPD patients. Moreover, 43% of the patients met the GOLD criteria for the diagnosis of COPD, whereas the Global Lung Function Initiative (GLI) and lower limit of normal (LLN)criteria were only able to identify 26%. DISCUSSION: COPD-related mortality is continuing to rise, and it is currently ranked as the third leading cause of death, globally, after cardiovascular diseases and strokes. Despite this alarming statistic, COPD diagnosis is delayed in most cases and can remain undiagnosed, even in smokers. This is partly due to the restrictive GOLD diagnostic criteria, which requires the presence of FEV

conclusionsThe recently proposed COPD Genetic Epidemiology (COPDGene

Indexed as

chronic obstructive pulmonary diseaseCOPDGeneGOLDpulmonary function testspirometry

Identifiers

PMID34236778
PMCPMC8428596

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.