Evidence map›Paper›PMID 34236658›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Glycan Compositions with GlyConnect Compozitor to Enhance Glycopeptide Identification.

Julien Mariethoz, Catherine Hayes, Frédérique Lisacek

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. PNGaseF-Generated N-Glycans Adduct onto Peptides in the Gas Phase.Journal of the American Society for Mass Spectrometry · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julien MariethozProteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland.
Catherine HayesProteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland.
Frédérique LisacekProteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland. frederique.lisacek@sib.swiss.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycoproteomics is unquestionably on the rise and its current development benefits from past experience in proteomics, in particular when attending to bioinformatics needs. An extensive range of software solutions is available, but the reproducibility of mass spectrometry data processing remains challenging. One of the key issues in running automated glycopeptide identification software is the selection of a reference glycan composition file. The default choices are often too broad, and a fastidious literature search to properly target this selection can be avoided. This chapter suggests the use of GlyConnect Compozitor to collect relevant information on glycosylation in a given tissue or cell line and shape an appropriate glycan composition set that can be input in the majority of search engines accommodating user-defined compositions.

Indexed as

GlycopeptidesPolysaccharidesProteomicsReproducibility of ResultsSoftwareTandem Mass SpectrometryGlycopeptidesPolysaccharidesDatabaseGlycanGlycopeptide identificationGlycosylationSoftware

Identifiers

PMID34236658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.