SynthesisJournal of autism and developmental disorders2022
Parent-Mediated Interventions for Infants under 24 Months at Risk for Autism Spectrum Disorder: A Systematic Review of Randomized Controlled Trials.
Synthesis in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Comparative efficacy of an early intervention "parent and me" program for infants showing signs of autism: The Baby JASPER model.Infant behavior & development · 2024Trial
- Short-term outcomes and six-month follow-up of BEAR: a blended, pre-emptive intervention for infants and toddlers at elevated likelihood for autism.European child & adolescent psychiatry · 2026Article
- Advances in supporting development in autistic children and youth.BMJ (Clinical research ed.) · 2026Review
- Risk factors for developmental delays in small for gestational age children at age of 24-36 months.European child & adolescent psychiatry · 2026Article
- Roles of genetic and environmental factors in psychiatric comorbidities among children with neurodevelopmental delays.World journal of psychiatry · 2025Article
- A pilot evaluation of the Baby Social ABCs caregiver-mediated intervention for 6-15-month-olds with early signs of autism-feasibility, acceptability, and preliminary evidence.Frontiers in child and adolescent psychiatry · 2025Article
- Parent attitudes towards predictive testing for autism in the first year of life.Journal of neurodevelopmental disorders · 2024Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prodromal symptoms of Autism Spectrum Disorder (ASD) have been detected within the first year of life. This review evaluated evidence from randomized controlled trials (RCTs) of parent-mediated interventions for infants under 24 months who are at risk for ASD. Electronic databases, including grey literature, were searched up till November 2019. Seven RCTs were identified. There was substantial heterogeneity in recruitment, outcome measures and effect size calculations. Interventions did not reduce the risk of later ASD diagnosis and post-intervention effects on infant outcomes were inconsistent, with five studies reporting significant improvements across both treatment and control groups. Moderate level of evidence of intervention effects on parental interaction skills and the small number of RCTs, and significant limitations restrict generalizability across studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.