Evidence map›Paper›PMID 34236475›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2021

Relationships between retinal structure and function and vision-related quality of life measures in advanced age-related macular degeneration.

Faran Sabeti, Jo Lane, Emilie M F Rohan, Rohan W Essex, Elinor McKone, Ted Maddess

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Genetic context modulates aging and degeneration in the murine retina.bioRxiv : the preprint server for biology · 2024
    Article
  4. Structure-Function Relationship in Keratoconus: Spatial and Depth Vision.Translational vision science & technology · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faran SabetiJohn Curtin School of Medical Research (JCSMR), The Australian National University, ACT, Canberra, Australia. faran.sabeti@canberra.edu.au.ORCID http://orcid.org/0000-0001-9187-7569
Jo LaneResearch School of Psychology, The Australian National University, Canberra, ACT, Australia.
Emilie M F RohanJohn Curtin School of Medical Research (JCSMR), The Australian National University, ACT, Canberra, Australia.
Rohan W EssexThe Canberra Hospital, Canberra, Australia.
Elinor McKoneResearch School of Psychology, The Australian National University, Canberra, ACT, Australia.
Ted MaddessJohn Curtin School of Medical Research (JCSMR), The Australian National University, ACT, Canberra, Australia.

Funding

Rebecca L. Cooper Medical Research Foundation PG2018040
6 · The paper itself

Abstract

purposeTo evaluate the association between ophthalmic structure/function measures and five standardized quality of life (QoL) instruments, in patients with advanced age-related macular degeneration (AMD).

methodsWe examined 20 AMD patients (ages 66-93 years) recruited from the Canberra Hospital Ophthalmology Department. Visual function measures included low and high contrast visual acuity (LCVA and HCVA) and measures from 10-2 Matrix visual fields (VF). Optical coherence tomography (OCT) quantified central retinal thickness (CRT), average macular thickness (AT), and retinal nerve fibre layer thickness (RNFL). The QoL instruments were the macular degeneration-related quality of life (MacDQoL), the National Eye Institute Visual Functioning Questionnaire (VFQ), its two face-recognition questions (A6 and 11), and the Geriatric Depression Scale (GDS). Pearson correlations, Canonical Correlation Analysis (CCA), and cross-validated stepwise-regression were used to examine the relationships between structure/function measures and the QoL instruments.

resultsThe selected models for the five instruments had R

conclusionsIn patients with advanced AMD, CRT and HCVA were strong determinants of QoL instruments in AMD patients.

Indexed as

Macular DegenerationQuality of LifeAgedAged, 80 and overCross-Sectional StudiesHumansRetinaSurveys and QuestionnairesTomography, Optical CoherenceVisual AcuityAge-related macular degenerationQuality of lifeRetinal functionRetinal structure

Identifiers

PMID34236475

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.