Evidence map›Paper›PMID 34236244›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Clinical characteristics, risk factors, and cardiac manifestations of cancer patients with COVID-19.

Yan Huang, Zhenhong Hu, Dong Hu, Zhou Quan, Xiaoyang Zhou, Guohua Fan, Xiu Chen, Xiaoxiong Liu, Zhonghe Zhang, Ganxiao Chen and 10 more

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Yan HuangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Zhenhong HuDepartment of Respiratory Medicine, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, Hubei, China.
Dong HuCenter for Stem Cell Research and Application, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhou QuanDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Xiaoyang ZhouDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Guohua FanDepartment of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Xiu ChenDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Xiaoxiong LiuDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Zhonghe ZhangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Ganxiao ChenDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yanwen WuDepartment of Respiratory Medicine, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, Hubei, China.
Fangqi ZhangDepartment of Respiratory Medicine, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, Hubei, China.
Congzheng MaoDepartment of Respiratory Medicine, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, Hubei, China.
Hao XiaDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Jinjun LiangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Bo YangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Hong JiangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Congxin HuangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Hector Barajas-MartínezLankenau Institute for Medical Research, Lankenau Heart Institute, Wynnewood, Pennsylvania.
Dan HuDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.ORCID 0000-0002-0994-8434
Wuhan University · CNGeneral Hospital of Central Theater CommandUnion Hospital · CNLankenau Institute for Medical Research · US

Funding

MOE | Fundamental Research Funds for the Central Universities (Fundamental Research Fund for the Central Universities) NO.2042019kf0058National Natural Science Foundation of China (NSFC) No. 81670304
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been associated with cardiovascular features, which may be deteriorated in patients with cancer. However, cardiac outcomes of cancer patients with COVID-19 have not been closely examined. We retrospectively assessed 1,244 patients with COVID-19 from February 1 to August 31, 2020 (140 cancer and 1,104 noncancer patients). Demographic and clinical data were obtained and compared between cancer and noncancer groups. Including the cardiac biomarkers, we also analyzed laboratory findings between these two groups. Risk factors for in-hospital mortality were identified by multivariable Cox regression models. For cancer group, 56% were in severe and critical status with more diabetes and immune deficiency, whereas the proportion was 10% for noncancer group. Patients with cancer had increased levels of leukocyte, neutrophil count, and blood urea nitrogen (BUN) (all

Indexed as

COVID-19NeoplasmsHumansRetrospective StudiesRisk FactorsSARS-CoV-2biomarkercardio-oncologyCOVID-19heart failurerisk factors

Identifiers

PMID34236244
PMCPMC8422422
OpenAlexW3182232455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.