Evidence map›Paper›PMID 34236243›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Carotid sinus nerve transection abolishes the facilitation of breathing that occurs upon cessation of a hypercapnic gas challenge in male mice.

Paulina M Getsy, Sripriya Sundararajan, Stephen J Lewis

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Paulina M GetsyDepartment of Pediatrics, Case Western University, Cleveland, Ohio.
Sripriya SundararajanPediatric Respiratory Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
Stephen J LewisDepartment of Pediatrics, Case Western University, Cleveland, Ohio.ORCID 0000-0001-7050-0666
Case Western Reserve University · USUniversity of Virginia · US

Funding

S-nitrosothiol signaling in pulmonary epithelial cellsP01HL101871 · NHLBI · UNIVERSITY OF VIRGINIA · PI GASTON, BENJAMIN, LEWIS, STEPHEN JOHN · 2011 to 2015
$8.7M
NHLBI NIH HHS P01 HL101871NHLBI NIH HHS PO1HL101871
6 · The paper itself

Abstract

Arterial pCO

Indexed as

Carotid BodyCarotid SinusAnimalsHypercapniaHypoxiaMaleMiceMice, Inbred C57BLRespirationC57BL6 micecarotid sinus chemoafferentshypercapniaventilatory parameters

Identifiers

PMID34236243
PMCPMC8409918
OpenAlexW3178181047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.