Evidence map›Paper›PMID 34236123›Full record

ArticleNeurogastroenterology and motility2022

Do resistance exercises during biofeedback therapy enhance the anal sphincter and pelvic floor muscles in anal incontinence?

Lori J Tuttle, Ali Zifan, Jessica Swartz, Ravinder K Mittal

Open access · greenAbstract read
In one paragraph

Article in Neurogastroenterology and motility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lori J TuttleDoctor of Physical Therapy Program, School of Exercise & Nutritional Sciences, San Diego State University, San Diego, California, USA.ORCID 0000-0002-1704-2747
Ali ZifanDivision of Gastroenterology, Department of Medicine, University of California San Diego, San Diego, California, USA.
Jessica SwartzDoctor of Physical Therapy Program, School of Exercise & Nutritional Sciences, San Diego State University, San Diego, California, USA.
Ravinder K MittalDivision of Gastroenterology, Department of Medicine, University of California San Diego, San Diego, California, USA.ORCID 0000-0001-5228-9617
San Diego State University · USUniversity of California San Diego · US

Funding

An Innovative Rehabilitation Approach for Women with Anal IncontinenceR01HD088688 · NICHD · SAN DIEGO STATE UNIVERSITY · PI TUTTLE, LORI J · 2017 to 2021
$2.6M
NICHD NIH HHS R01 HD088688
6 · The paper itself

Abstract

aimTo determine if a biofeedback therapy that includes concentric resistance exercise for the anal sphincter muscles can improve muscle strength/function and improve AI symptoms compared to the traditional/non-resistance biofeedback therapy.

backgroundBiofeedback therapy is the current gold standard treatment for patients with anal incontinence (AI). Lack of resistance exercise biofeedback programs is a limitation in current practice.

methodsThirty-three women with AI (mean age 60 years) were randomly assigned to concentric (resistance) or isometric (non-resistance) biofeedback training. Concentric training utilized the Functional Luminal Imaging Probe to provide progressive resistance exercises based on the patient's ability to collapse the anal canal lumen. Isometric training utilized a non-collapsible 10 mm diameter probe. Both groups performed a biofeedback protocol once per week in the clinic for 12 weeks and at home daily. High definition anal manometry was used to assess anal sphincter strength; symptoms were measured using FISI and UDI-6. 3D transperineal ultrasound imaging was used to assess the anal sphincter muscle integrity.

resultsConcentric and isometric groups improved FISI and UDI-6 scores to a similar degree. Both the concentric and isometric groups showed small improvement in the anal high-pressure zone; however, there was no difference between the two groups. Ultrasound image analysis revealed significant damage to the anal sphincter muscles in both patient groups.

conclusionsConcentric resistance biofeedback training did not improve the anal sphincter muscle function or AI symptoms beyond traditional biofeedback training. Anal sphincter muscle damage may be an important factor that limits the success of biofeedback training.

Indexed as

AdultAgedAged, 80 and overAnal CanalBiofeedback, PsychologyFecal IncontinenceFemaleHumansMaleMiddle AgedMuscle, SmoothPelvic FloorResistance Traininganal sphincterbiofeedbackfecal incontinencepelvic floorstrength training

Identifiers

PMID34236123
PMCPMC8712345
OpenAlexW3177694021

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.