Evidence map›Paper›PMID 34235940›Full record

ArticleBone & joint research2021

Osseointegration of retrieved 3D-printed, off-the-shelf acetabular implants.

Lorenzo Dall'Ava, Harry Hothi, Johann Henckel, Anna Di Laura, Roberto Tirabosco, Antti Eskelinen, John Skinner, Alister Hart

Abstract read
In one paragraph

Article in Bone & joint research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. [Hip surgery: 3D printed implants in revision arthroplasty].Orthopadie (Heidelberg, Germany) · 2025
    Review
  6. Review
  7. [Research progress of three-dimensional printed customized prosthesis and its application in acetabular reconstruction of hip revision surgery].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Point-of-Care Orthopedic Oncology Device Development.Current oncology (Toronto, Ont.) · 2023
    Article
  12. Comparative studyWorld journal of orthopedics · 2023
    Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lorenzo Dall'AvaInstitute of Orthopaedics and Musculoskeletal Science, Division of Surgery and Interventional Science, University College London, Stanmore, UK.
Harry HothiRoyal National Orthopaedic Hospital NHS Trust, Stanmore, UK.
Johann HenckelRoyal National Orthopaedic Hospital NHS Trust, Stanmore, UK.
Anna Di LauraRoyal National Orthopaedic Hospital NHS Trust, Stanmore, UK.
Roberto TiraboscoDepartment of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, UK.
Antti EskelinenThe Coxa Hospital for Joint Replacement, Tampere, Finland.
John SkinnerRoyal National Orthopaedic Hospital NHS Trust, Stanmore, UK.
Alister HartInstitute of Orthopaedics and Musculoskeletal Science, Division of Surgery and Interventional Science, University College London, Stanmore, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe main advantage of 3D-printed, off-the-shelf acetabular implants is the potential to promote enhanced bony fixation due to their controllable porous structure. In this study we investigated the extent of osseointegration in retrieved 3D-printed acetabular implants.

methodsWe compared two groups, one made via 3D-printing (n = 7) and the other using conventional techniques (n = 7). We collected implant details, type of surgery and removal technique, patient demographics, and clinical history. Bone integration was assessed by macroscopic visual analysis, followed by sectioning to allow undecalcified histology on eight sections (~200 µm) for each implant. The outcome measures considered were area of bone attachment (%), extent of bone ingrowth (%), bone-implant contact (%), and depth of ingrowth (%), and these were quantified using a line-intercept method.

resultsThe two groups were matched for patient sex, age (61 and 63 years), time to revision (30 and 41 months), implant size (54 mm and 52 mm), and porosity (72% and 60%) (p > 0.152). There was no difference in visual bony attachment (p = 0.209). Histological analysis showed greater bone ingrowth in 3D-printed implants (p < 0.001), with mean bone attachment of 63% (SD 28%) and 37% (SD 20%), respectively. This was observed for all the outcome measures.

conclusionThis was the first study to investigate osseointegration in retrieved 3D-printed acetabular implants. Greater bone ingrowth was found in 3D-printed implants, suggesting that better osseointegration can be achieved. However, the influence of specific surgeon, implant, and patient factors needs to be considered. Cite this article:

Indexed as

3D-printingAdditive manufacturingHip arthroplastyOsseointegrationRetrieval analysis

Identifiers

PMID34235940
PMCPMC8333029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.