Evidence map›Paper›PMID 34235899›Full record

ReviewJournal of biomedical optics2021

Optical manipulation: advances for biophotonics in the 21st century.

Stella Corsetti, Kishan Dholakia

Abstract readReview
In one paragraph

Review in Journal of biomedical optics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Diamond Metasurface-Based Optical Tweezers With Enhanced Robustness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Hypothermal opto-thermophoretic tweezers.Nature communications · 2023
    Article
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  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stella CorsettiScottish Universities Physics Alliance, Univ. of St. Andrews, Univ. of St. Andrews, United Kingdom.
Kishan DholakiaScottish Universities Physics Alliance, Univ. of St. Andrews, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significanceOptical trapping is a technique capable of applying minute forces that has been applied to studies spanning single molecules up to microorganisms.

aimThe goal of this perspective is to highlight some of the main advances in the last decade in this field that are pertinent for a biomedical audience. APPROACH: First, the direct determination of forces in optical tweezers and the combination of optical and acoustic traps, which allows studies across different length scales, are discussed. Then, a review of the progress made in the direct trapping of both single-molecules, and even single-viruses, and single cells with optical forces is outlined. Lastly, future directions for this methodology in biophotonics are discussed.

resultsIn the 21st century, optical manipulation has expanded its unique capabilities, enabling not only a more detailed study of single molecules and single cells but also of more complex living systems, giving us further insights into important biological activities.

conclusionsOptical forces have played a large role in the biomedical landscape leading to exceptional new biological breakthroughs. The continuous advances in the world of optical trapping will certainly lead to further exploitation, including exciting in-vivo experiments.

Indexed as

NanotechnologyOptical Tweezersbiophotonicslightoptical manipulationoptical tweezersopticstrapping

Identifiers

PMID34235899
PMCPMC8262092

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.