Evidence map›Paper›PMID 34235492›Full record

ArticleCurrent research in structural biology2021

Calmodulin complexes with brain and muscle creatine kinase peptides.

Janina Sprenger, Anda Trifan, Neal Patel, Ashley Vanderbeck, Jenny Bredfelt, Emad Tajkhorshid, Roger Rowlett, Leila Lo Leggio, Karin S Åkerfeldt, Sara Linse

Open access · goldAbstract read
In one paragraph

Article in Current research in structural biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Retinal Cyclic Nucleotide-Gated Channel Regulation by Calmodulin.International journal of molecular sciences · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Janina SprengerDepartment of Biochemistry and Structural Biology, Chemical Center, PO Box 124, SE-221 00, Lund, Sweden.
Anda TrifanTheoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, 405 N Matthews, Urbana, IL, 61801, USA.
Neal PatelDepartment of Chemistry, Haverford College, 370 Lancaster Avenue, Haverford, PA, 19041, USA.
Ashley VanderbeckDepartment of Chemistry, Haverford College, 370 Lancaster Avenue, Haverford, PA, 19041, USA.
Jenny BredfeltDepartment of Biochemistry and Structural Biology, Chemical Center, PO Box 124, SE-221 00, Lund, Sweden.
Emad TajkhorshidTheoretical and Computational Biophysics Group, NIH Center for Macromolecular Modeling and Bioinformatics, Beckman Institute for Advanced Science and Technology, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, 405 N Matthews, Urbana, IL, 61801, USA.
Roger RowlettDepartment of Chemistry, Colgate University, 13 Oak Drive, Hamilton, NY, 13346, USA.
Leila Lo LeggioChemistry Department, University of Copenhagen, Universitetsparken 5, 2100, Copenhagen, Denmark.
Karin S ÅkerfeldtDepartment of Chemistry, Haverford College, 370 Lancaster Avenue, Haverford, PA, 19041, USA.
Sara LinseDepartment of Biochemistry and Structural Biology, Chemical Center, PO Box 124, SE-221 00, Lund, Sweden.
Haverford College · USUniversity of Copenhagen · DKUniversity of Illinois Urbana-Champaign · USColgate University · US

Funding

VMD-PhD Training in Infectious Disease-Related ResearchT32AI070077 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Michael Lee Atchison · 2008 to 2026
$3.5M
NIAID NIH HHS T32 AI070077
6 · The paper itself

Abstract

Calmodulin (CaM) is a ubiquitous Ca

Indexed as

ADP, Adenosine diphosphateATP, Adenosine triphosphateCa2+, Calcium ion (divalent)Calcium signalingCalmodulin X-ray structureCaM, CalmodulinCellular energy metabolismCKB, Creatine kinase, brain-typeCK, Creatine kinaseCKM, Creatine kinase, muscle-typeCr, CreatineCrP, Creatine phosphateEnzyme regulationFmoc, FluorenylmethoxycarbonylIsothermal titration calorimetryITC, Isothermal titration calorimetryMR, Molecular replacementPDB, Protein data bank

Identifiers

PMID34235492
PMCPMC8244255
OpenAlexW3163119190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.