Evidence map›Paper›PMID 34235405›Full record

ArticlemicroPublication biology2021

The conserved MASRPF motif in the Attractin homolog, Distracted, is required for association with Drosophila E3-ligase Mgrn1.

Vindhya Nawaratne, Sirisha Kudumala, Priyanka Prakash Kakad, Tanja A Godenschwege

Open access · greenAbstract read
In one paragraph

Article in microPublication biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. "Design principles of a membrane-spanning ubiquitin ligase".bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Vindhya NawaratneBiological Science Department, Florida Atlantic University, Jupiter, FL 33458.
Sirisha KudumalaProdigy Biotech, Jupiter, FL 33458.
Priyanka Prakash KakadScienCell Research Laboratories, Inc., 1610 Faraday Avenue, Carlsbad, CA 92008.
Tanja A GodenschwegeBiological Science Department, Florida Atlantic University, Jupiter, FL 33458.
Florida Atlantic University · USFaraday Technology (United States) · USJupiter Medical Center · US

Funding

Nuclear function of L1-type CAMs in the drosophila nervous systemR15NS090043 · NINDS · FLORIDA ATLANTIC UNIVERSITY · PI GODENSCHWEGE, TANJA ANGELA · 2015 to 2015
$448k
NINDS NIH HHS R15 NS090043
6 · The paper itself

Abstract

In rodents, all three paralogs of the Attractin (Atrn) transmembrane protein family exhibit strong phenotypic overlap and are implicated in the regulation of the same G-protein coupled receptors (GPCR) as E3-ligase Mahogunin ring finger 1 (Mgrn1). Recently it was shown that the highly conserved intracellular MASRPF motif in mammal Multiple epidermal growth factor-like domain 8 protein is required for binding of Mgrn1 to mediate ubiquitination of GPCR Smoothened in vitro. Here, we show that the MASRPF motif of

Identifiers

PMID34235405
PMCPMC8254101
OpenAlexW3182111930

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.