Evidence map›Paper›PMID 34235373›Full record

ArticleCurrent developments in nutrition2021

Longer Leukocyte Telomere Length Predicts Stronger Response to a Workplace Sugar-Sweetened Beverage Sales Ban: An Exploratory Study.

Janet M Wojcicki, Robert H Lustig, Laurie M Jacobs, Ashley E Mason, Alison Hartman, Cindy Leung, Kimber Stanhope, Jue Lin, Laura A Schmidt, Elissa S Epel

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current developments in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02585336 (Effects of Sugar-sweetened Beverage Consumption Changes on Metabolic Health), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02585336 nacompletednot on this map

Effects of Sugar-sweetened Beverage Consumption Changes on Metabolic Health: Improving Metabolic Profile Very Effortlessly (IMPROVE)

TypeinterventionalSponsorUniversity of California, San FranciscoRan2015 to 2016Enrolled214ConditionsMetabolic HealthArmsBrief intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Janet M WojcickiDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Robert H LustigDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Laurie M JacobsPhilip R Lee Institute for Health Policy Studies, University of California, San Francisco, CA, USA.
Ashley E MasonDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, USA.
Alison HartmanCenter for Health and Community, University of California, San Francisco, CA, USA.
Cindy LeungDepartment of Nutritional Science, School of Public Health, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0000-0001-6718-3487
Kimber StanhopeDepartment of Molecular Biosciences, University of California, Davis, CA, USA.
Jue LinDepartment of Biophysics and Biochemistry, University of California, San Francisco, CA, USA.
Laura A SchmidtPhilip R Lee Institute for Health Policy Studies, University of California, San Francisco, CA, USA.
Elissa S EpelDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, USA.
University of California, San Francisco · USLee University · USUniversity of California, Davis · USUniversity of Michigan · US

Funding

UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30 DK098722
6 · The paper itself

Abstract

backgroundShorter leukocyte telomere length (LTL) is associated with increased risk of a number of metabolic diseases including insulin resistance and the development of type 2 diabetes mellitus. Shorter LTL is also associated with stress reactivity suggestive of a possible role for LTL to predict response to behavioral interventions. However, few studies have evaluated how interventions, such as weight loss or dietary changes, are associated with LTL changes or whether LTL can predict behavioral responses to interventions.

objectivesWe evaluated metabolic changes in relation to LTL changes and LTL at baseline in a cohort of at-risk adults in response to a 10-mo workplace-based sugar-sweetened beverage (SSB) intervention.

methodsAt baseline, metabolic health and LTL measurements were assessed through standard blood draws on 212 participants. Multivariable linear regression models were used to assess changes in anthropometrics, SSB consumption, and 13 blood-based metabolic risk factors, in relation to LTL at baseline and changes in LTL.

resultsLonger LTL at baseline was associated with decreases in SSB consumption over the 6-mo follow-up period (B = -29.67;

conclusionsLonger LTL at baseline predicted a favorable overall response to a behavioral intervention: decreases in SSB consumption. Abdominal adiposity losses paralleled slower declines in LTL suggestive of overall health benefits, but we found differences in the relations between metabolic changes and LTL at baseline compared with LTL attrition rates. Longer LTL may be a proxy marker of a positive behavioral response.This trial was registered at clinicaltrials.gov as NCT02585336.

Indexed as

adipositycommunity level interventionlipidsSSBsugar-sweetened beveragestelomerewaist circumference

Identifiers

PMID34235373
PMCPMC8257411
OpenAlexW3165228963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.