Evidence map›Paper›PMID 34235346›Full record

ArticlePediatric quality & safety

Reducing Time to Discharge after Chemotherapy by Standardizing Workflow and Providing Outpatient Intravenous Hydration.

Jitsuda Sitthi-Amorn, Allison Ast, Erin Harper, Brian Abbott, Yaser Alsaek, Wendy Bourland, Rachael Courtney, Arshia Madni, Aditya Sharma, Christopher Spencer and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Pediatric quality & safety. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Jitsuda Sitthi-AmornHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Allison AstHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Erin HarperHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Brian AbbottPRA Health Sciences, Raleigh, N.C.
Yaser AlsaekHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Wendy BourlandHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Rachael CourtneyHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Arshia MadniHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Aditya SharmaHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
Christopher SpencerDepartment of Nursing, St. Jude Children's Research Hospital, Memphis, Tenn.
Lane McCurrachDepartment of Nursing, St. Jude Children's Research Hospital, Memphis, Tenn.
Stacey MorganDivision of Pediatric Nephrology, Department of Pediatrics, Le Bonheur Children's Hospital, Memphis, Tenn.
John McCormickDepartment of Pharmaceutical Services, St. Jude Children's Research Hospital, Memphis, Tenn.
David WittmanOffice of Quality and Patient Care, St. Jude Children's Research Hospital, Memphis, Tenn.
Liza-Marie JohnsonHospitalist Medicine Program, St. Jude Children's Research Hospital, Memphis, Tenn.
St. Jude Children's Research Hospital · USLe Bonheur Children's Hospital · USPRA Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients receiving cyclophosphamide or ifosfamide chemotherapy require intravenous fluid hydration to prevent hemorrhagic cystitis. In selected patients without medical contraindications (ie, excess nausea/vomiting), this hydration may be completed after discharge. We aimed to reduce the time to discharge after completing mesna in patients receiving cyclophosphamide or ifosfamide therapy on an inpatient chemotherapy service.

methodsThe quality improvement team performed a medical record review to capture the time to discharge after mesna therapy and the readmission rate and used quality improvement methods to redesign discharge workflow and increase patient involvement with the discharge process.

resultsFrom August 2017 through July 2018, there were 160 admission encounters (73 patients) for cyclophosphamide or ifosfamide on a dedicated chemotherapy service. Of those encounters, 89 (55.6%) were appropriate for outpatient hydration; 48 (53.9%) of these encounters involved a patient who elected to receive outpatient hydration. Although the median time to discharge for the whole cohort did not change, in encounters where patients chose intravenous outpatient hydration, the median time to discharge was reduced from 2.82 to 0.66 hours (76.6% reduction) after implementing the new discharge workflow. No patients experienced readmission within 48 hours.

conclusionsDischarge workflow redesign and standardization reduced the time to discharge after chemotherapy in patients who chose outpatient hydration. Outpatient intravenous hydration after cyclophosphamide or ifosfamide appears safe and feasible in selected patient populations.

Identifiers

PMID34235346
PMCPMC8225375
OpenAlexW3176183610

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.