Evidence map›Paper›PMID 34235293›Full record

ArticleClinical neurophysiology practice2021

Auditory brainstem responses in adults with autism spectrum disorder.

H Fujihira, C Itoi, S Furukawa, N Kato, M Kashino

Open access · goldAbstract read
In one paragraph

Article in Clinical neurophysiology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. How auditory processing influences the autistic profile: A review.Autism research : official journal of the International Society for Autism Research · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

H FujihiraNTT Communication Science Laboratories, Morinosato Wakamiya, Atsugi, Kanagawa, Japan.
C ItoiDepartment of Psychology, Faculty of Letters, Chuo University, Higashinakano, Hachioji, Tokyo, Japan.
S FurukawaNTT Communication Science Laboratories, Morinosato Wakamiya, Atsugi, Kanagawa, Japan.
N KatoMedical Institute of Developmental Disabilities Research, Showa University, Kitakarasuyama, Setagaya, Tokyo, Japan.
M KashinoNTT Communication Science Laboratories, Morinosato Wakamiya, Atsugi, Kanagawa, Japan.
Chuo University · JPJapan Society for the Promotion of Science · JPShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate possible differences in the auditory peripheral and brainstem functions between adults with autism spectrum disorder (ASD) and neurotypical (NT) adults.

methodsClick-evoked auditory brainstem responses (ABRs) were obtained from 17 high-functioning ASD adults (aged 21-38 years) and 20 NT adults (aged 22-36 years). A relatively large number of stimulus presentations (6000) were adopted, and ABRs by horizontal and vertical electrode montages were evaluated, in order to allow precise evaluations of early ABR components.

resultsWaves I, II, III, and V were identified in the vertical electrode montage, and wave I and the summating potential (SP) in electrocochleograms were identified in the horizontal electrode montage. There were no significant group differences in the wave I, II, III, and V latencies or the interpeak latencies (IPLs) in the vertical electrode montage. In the horizontal montage, the ASD adults exhibited significantly shortened SP latencies compared with the NT adults, whereas there was no significant group difference in the wave I latency.

conclusionThe ASD adults may have the abnormalities of processing more in the peripheral auditory system than in the brainstem. SIGNIFICANCE: The current study suggests that the peripheral abnormality is associated with ASD.

Indexed as

Auditory brainstem responseAutism spectrum disorderPeripheral auditory systemSummating potential

Identifiers

PMID34235293
PMCPMC8249870
OpenAlexW3168726488

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.