Evidence map›Paper›PMID 34235281›Full record

ArticleHeliyon2021

Biological characteristics of a sub-population of cancer stem cells from two triple-negative breast tumour cell lines.

Javier Enciso-Benavides, Luis Alfaro, Carlos Castañeda-Altamirano, Nancy Rojas, José González-Cabeza, Nathaly Enciso, Fernando Riesco, Miluska Castillo, Javier Enciso

Abstract read
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Cancer Stem Cells from Definition to Detection and Targeted Drugs.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Water Extract Have Superior Cytotoxic Effect Than Ethanolic Extract of Clinacanthus Nutans Leaves in Breast Cancer Stem Cells.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Javier Enciso-BenavidesLaboratorio de Células Madre, Clínica Veterinaria Enciso, Lima, Peru.
Luis AlfaroGrupo de Medicina Regenerativa, Universidad Científica del Sur, Lima, Peru.
Carlos Castañeda-AltamiranoInstituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Nancy RojasLaboratorio de Microscopia Electrónica, Instituto de Patología, UNMSM, Lima, Peru.
José González-CabezaUniversidad Privada Antenor Orrego, Trujillo, Peru.
Nathaly EncisoDirección General de Investigación, Desarrollo e Innovación, Universidad Científica del Sur, Lima, Peru.
Fernando RiescoLaboratorio de Microscopia Electrónica, Instituto de Patología, UNMSM, Lima, Peru.
Miluska CastilloInstituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Javier EncisoGrupo de Medicina Regenerativa, Universidad Científica del Sur, Lima, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast tumours (TNBTs) make up 15-20% of all breast tumours. There is no treatment for them, and the role that cancer stem cells (CSCs) have in carcinogenesis is still unclear, so finding markers and therapeutic targets in CSC exosomes requires these cells to exist as a homogeneous cell population. The objective of this work was to determine differences in ultrastructural morphology, proliferative capacity, and mouse-xenotransplantation characteristics of the MDA-MB-231 and MDA-MB-436 TNBT cell lines with the CD44

Indexed as

Cancer stem cellsCD44high/CD24low phenotype cellsMagnetic immunoselectionTriple-negative breast tumors

Identifiers

PMID34235281
PMCPMC8247099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.