Evidence map›Paper›PMID 34235244›Full record

ArticleInternational journal of cardiology. Heart & vasculature2021

Sex differences in Cardiac electronic device implantation: Outcomes from an Australian multi-centre clinical quality registry.

David Eccleston, Daniel Cehic, Glenn Young, Tina Lin, Steven Pavia, Enayet K Chowdhury, Christopher Reid, Danny Liew, Ben King, Isabel Tan and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

David EcclestonWarringal Private Hospital, Melbourne, Australia.
Daniel CehicWakefield Hospital, Adelaide, Australia.
Glenn YoungWakefield Hospital, Adelaide, Australia.
Tina LinWarringal Private Hospital, Melbourne, Australia.
Steven PaviaWesley Hospital, Brisbane, Australia.
Enayet K ChowdhurySchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Christopher ReidSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Danny LiewSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Ben KingMount Hospital, Perth, Australia.
Isabel TanMount Hospital, Perth, Australia.
Karen PhillipsWesley Hospital, Brisbane, Australia.
David O'DonnellWarringal Private Hospital, Melbourne, Australia.
GenesisCare Outcomes Registry Investigators
Calvary Wakefield Hospital · AUCurtin University · AUMonash University · AUMount Medical Centre · AUWesley Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is uncertainty regarding whether outcomes after Cardiac Implantable Electronic Devices (CIED) differ between women and men. There are no prospectively collected data regarding Australian CIED outcomes. This study aimed to determine whether the characteristics and outcomes of Australian patients undergoing CIED implantation differ by sex.

methodsWe prospectively followed 5,360 patients undergoing CIED implantation between 2015 and 2019 in a large multi-centre Australian registry. Patient characteristics, procedural data, medications and clinical outcomes to 1 year were analysed.

resultsThe mean age was 76.2 + 11.2 years, and 2022 (37.7%) were female. Women were older than men at device implantation (77.0 ± 11.6 years vs. 75.5 ± 10.9 years, p < 0.001). Most implants were de novo (79.7%). Pacing was more commonly for sick sinus syndrome in women than men (54.4% vs. 47.2%, p < 0.001) and less often for A-V block (28.3% vs. 35.1%, p < 0.001). Adverse events at 30 days were low compared to international cohorts, for mortality (0.06%) and major complications (0.6%). There were no significant sex differences (women vs. men) for death (HR 1.33, 95% CI 0.58-3.13, p = 0.49) or major complications (HR 1.41, 95% 95% CI 0.65-3.03, p = 0.39). At 1-year, there was no difference in major complications or risk-adjusted all-cause mortality (HR 1.05, 95% CI 0.70-1.29, p = 0.77) between women and men.

conclusionsClinical practice and 30-day outcomes after CIED implantation in Australia are consistent with international reports. There were no differences in procedural complication rates or clinical outcomes at 1-year between women and men, regardless of age or CIED system implanted.

Indexed as

AF, Atrial fibrillationA-V, Atrio-ventricularCABG, Coronary artery bypass graftCardiac Implantable Electronic DeviceCIED, Cardiac implantable electronic deviceCRT-P, Cardiac Resynchronisation therapy pacemakerDDD, Dual chamber sensing and pacingEPS, Electrophysiological studyGCOR, GenesisCare Cardiovascular Outcomes RegistryHF, Heart failureICD, Implantable cardioverter-defibrillatorILR, Implantable loop recorderMI, Myocardial infarctionNCDR, National Cardiovascular data registryNOAC, Non-Vitamin K-dependent Oral AnticoagulantOR, Odds ratioOutcomesPCI, Percutaneous coronary interventionPM, PacemakerQualityRegistrySexVDD, Ventricular sensing dual chamber pacingVT/VF, Ventricular tachycardia/fibrillationVVI, Ventricular sensing and pacing

Identifiers

PMID34235244
PMCPMC8246382
OpenAlexW3176353116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.