Evidence map›Paper›PMID 34235181›Full record

ReviewFrontiers in molecular biosciences2021

A Primer on the oxDNA Model of DNA: When to Use it, How to Simulate it and How to Interpret the Results.

A Sengar, T E Ouldridge, O Henrich, L Rovigatti, P Šulc

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. A nanoscale Jitterbug transformer from DNA.Nature communications · 2026
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  2. Fitting coarse-grained models to macroscopic experimental data via automatic differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  5. How We Simulate DNA Origami.Small methods · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A SengarCentre for Synthetic Biology, Department of Bioengineering, Imperial College London, London, United Kingdom.
T E OuldridgeCentre for Synthetic Biology, Department of Bioengineering, Imperial College London, London, United Kingdom.
O HenrichDepartment of Physics, SUPA, University of Strathclyde, Glasgow, United Kingdom.
L RovigattiDepartment of Physics, Sapienza University of Rome, Rome, Italy.
P ŠulcCenter for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, AZ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oxDNA model of Deoxyribonucleic acid has been applied widely to systems in biology, biophysics and nanotechnology. It is currently available via two independent open source packages. Here we present a set of clearly documented exemplar simulations that simultaneously provide both an introduction to simulating the model, and a review of the model's fundamental properties. We outline how simulation results can be interpreted in terms of-and feed into our understanding of-less detailed models that operate at larger length scales, and provide guidance on whether simulating a system with oxDNA is worthwhile.

Indexed as

biophysicscoarse-grained modellingdeoxyribonucleic acidmolecular simulation (molecular modeling)nanotechnology

Identifiers

PMID34235181
PMCPMC8256390

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.