Evidence map›Paper›PMID 34235044›Full record

ArticleClinical nephrology. Case studies2021

Light chain cast nephropathy caused by plasmablastic lymphoma of the bladder.

Mehrian Jafarizade, Kiran Goli, Vivette D'Agati, Essel Dulaimi, Krupa Daniel, Bradley Lash, Sharon Maynard

Open access · greenAbstract readCase Reports
In one paragraph

Article in Clinical nephrology. Case studies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mehrian JafarizadeDepartment of Medicine, Division of Nephrology, Lehigh Valley Health Network, Allentown, PA.
Kiran GoliDepartment of Medicine, Division of Nephrology, Lehigh Valley Health Network, Allentown, PA.
Vivette D'AgatiDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY.
Essel DulaimiDepartment of Anatomic Pathology, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA.
Krupa DanielDepartment of Geriatrics and Extended Care, VA Medical Center, Coatesville, PA, and.
Bradley LashLehigh Valley Cancer Institute, Lehigh Valley Health Network, Allentown, PA, USA.
Sharon MaynardDepartment of Medicine, Division of Nephrology, Lehigh Valley Health Network, Allentown, PA.
Lehigh Valley Hospital-Pocono · USCoatesville Veterans Affairs Medical Center · USPhiladelphia VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPlasmablastic lymphoma (PBL) is a rare form of B-cell lymphoma typically seen in patients with underlying immunosuppression such as HIV, autoimmune disease, and organ transplantation. PBL in HIV-positive patients usually originates from the gastrointestinal tract, with a predilection for the oral cavity. Bladder involvement by PBL is exceedingly rare, and cast nephropathy due to κ light chain-secreting PBL has not been reported previously. CASE REPORT: We report a patient who presented with acute kidney injury (AKI) in the setting of HIV, and was found to have a bladder tumor. Bladder pathology revealed a high-grade PBL with κ light chain restriction. Renal biopsy showed κ light chain cast nephropathy, presumably secondary to κ light chain-secreting PBL.

conclusionAlthough the prognosis of PBL is poor, our patient recovered from AKI, achieved complete hematologic remission with chemotherapy, and underwent successful autologous stem cell transplant.

Indexed as

acute kidney injurybladder lymphomaHIVinterstitial nephritislight chain cast nephropathylymphomaplasmablastic lymphoma

Identifiers

PMID34235044
PMCPMC8259465
OpenAlexW3180085413

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.