Evidence map›Paper›PMID 34234939›Full record

ArticleInternational journal of inflammation2021

Extended Inflammation Parameters (EIP) as Markers of Immune System Cell Activation in Psoriasis.

Anna Kowalska-Kępczyńska, Mateusz Mleczko, Weronika Domerecka, Marcin Mazurek, Dorota Krasowska, Teresa Małecka-Massalska, Helena Donica

Abstract read
In one paragraph

Article in International journal of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna Kowalska-KępczyńskaDepartment of Biochemical Diagnostics, Chair of Laboratory Diagnostics, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-6018-9437
Mateusz MleczkoChair and Department of Dermatology, Venerology and Paediatric Dermatology, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-7909-5713
Weronika DomereckaChair and Department of Human Physiology, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-7654-2573
Marcin MazurekChair and Department of Human Physiology, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-4040-0450
Dorota KrasowskaChair and Department of Dermatology, Venerology and Paediatric Dermatology, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-3176-9870
Teresa Małecka-MassalskaChair and Department of Human Physiology, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0003-3384-0324
Helena DonicaDepartment of Biochemical Diagnostics, Chair of Laboratory Diagnostics, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0003-0677-7825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is an inflammatory, autoimmune disease that affects approximately 2% of the population. The inflammation in psoriasis can be systemic, so despite a predominantly cutaneous manifestation, it also affects the internal organs. The diagnosis and monitoring of the disease are based on the clinical picture. To assess the disorders of other organs, additional tests need to be performed. Recently, the examination of blood morphology has been enriched with modern haematological parameters, i.e., Extended Inflammation Parameters (EIP), which include RE-LYMPH (activated lymphocytes), AS-LYMPH (antibody-producing B lymphocytes), and NEUT-RI and NEUT-GI (activated neutrophils). In the study, higher values of new haematological parameters were observed in individuals with psoriasis than in healthy controls. A higher EIP value was noted in the group of individuals with plaque psoriasis than in the group of individuals with psoriatic arthritis. Implementation of these parameters into routine laboratory analysis will likely make it possible to estimate the severity of the inflammation and improve its assessment.

Identifiers

PMID34234939
PMCPMC8219407

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.