Evidence map›Paper›PMID 34234877›Full record

ArticleDisease markers2021

Correlation between C-Reactive Protein to Albumin Ratio and Disease Activity in Patients with Axial Spondyloarthritis.

Zheng Zhong, Yukai Huang, Yuqi Liu, Junming Chen, Meng Liu, Qidang Huang, Shaoling Zheng, Xin Guo, Weiming Deng, Tianwang Li

Abstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
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  4. The association of C-reactive protein to albumin ratio wıth lichen planus.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zheng ZhongDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Yukai HuangDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Yuqi LiuDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Junming ChenDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Meng LiuDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Qidang HuangDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Shaoling ZhengDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Xin GuoDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Weiming DengDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.
Tianwang LiDepartment of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China.ORCID https://orcid.org/0000-0001-6438-2691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe C-reactive protein (CRP) to albumin (ALB) ratio (CAR) has emerged as a novel inflammatory biomarker. This study was designed to investigate the role of CAR in the disease activity of axial spondyloarthritis (axSpA).

methodsA total of 241 patients and 61 healthy controls were retrospectively enrolled in this study. AxSpA patients were further divided into the inactive group (

resultsIn axSpA patients, CAR was significantly higher than the healthy group (

conclusionsCAR was increased in axSpA and axSpA of the active group. CAR may be a novel and reliable indicator for axSpA disease activity.

Indexed as

Severity of Illness IndexAdultAxial SpondyloarthritisBiomarkersCase-Control StudiesC-Reactive ProteinCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedRetrospective StudiesSensitivity and SpecificitySerum AlbuminBiomarkersC-Reactive ProteinSerum Albumin

Identifiers

PMID34234877
PMCPMC8216814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.