Evidence map›Paper›PMID 34234861›Full record

ArticleJournal of Cancer2021

A clinical prediction model identifies a subgroup with inferior survival within intermediate risk acute myeloid leukemia.

Xiaoxia Hu, Bianhong Wang, Qi Chen, Aijie Huang, Weijia Fu, Lixia Liu, Ying Zhang, Gusheng Tang, Hui Cheng, Xiong Ni and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Decision-Making When Diagnostic Testing is Available.Cancer treatment and research · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Xiaoxia HuDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Bianhong WangDepartment of Hematology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China.
Qi ChenDepartment of Health Statistics, Second Military Medical University, Shanghai 200433, China.
Aijie HuangDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Weijia FuDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Lixia LiuAcornmed Biotechnology Co., Ltd. Beijing, 100176, China.
Ying ZhangDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Gusheng TangDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Hui ChengDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Xiong NiDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Lei GaoDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Jie ChenDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Li ChenDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Weiping ZhangDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Jianmin YangDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Shanbo CaoAcornmed Biotechnology Co., Ltd. Beijing, 100176, China.
Li YuDepartment of Hematology, Chinese PLA General Hospital, Beijing, 100853, China.
Jianmin WangDepartment of Hematology, Institute of Hematology, Changhai Hospital, Shanghai 200433, China.
Changhai Hospital · CNSecond Military Medical University · CNChinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intermediate risk acute myeloid leukemia (AML) comprises around 50% of AML patients and is featured with heterogeneous clinical outcomes. The study aimed to generate a prediction model to identify intermediate risk AML patients with an inferior survival. We performed targeted next generation sequencing analysis for 121 patients with 2017 European LeukemiaNet-defined intermediate risk AML, revealing 122 mutated genes, with 24 genes mutated in > 10% of patients. A prognostic nomogram characterized by white blood cell count ≥10×10

Indexed as

Acute myeloid leukemiaallogenic hematopoietic stem cell transplantationIntermediate riskNomogramPrediction model

Identifiers

PMID34234861
PMCPMC8247394
OpenAlexW3176095772

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.