Evidence map›Paper›PMID 34234831›Full record

ReviewDrugs in context2021

Therapeutics for paediatric oncological emergencies.

Karen Ka Yan Leung, Kam Lun Hon, Wun Fung Hui, Alexander Kc Leung, Chi Kong Li

Open access · goldAbstract readReview
In one paragraph

Review in Drugs in context, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Karen Ka Yan LeungPaediatric Intensive Care Unit, Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong.ORCID https://orcid.org/0000-0002-6689-7194
Kam Lun HonPaediatric Intensive Care Unit, Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong.ORCID https://orcid.org/0000-0002-6682-5529
Wun Fung HuiPaediatric Intensive Care Unit, Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong.ORCID https://orcid.org/0000-0001-5941-1478
Alexander Kc LeungDepartment of Pediatrics, The University of Calgary and The Alberta Children's Hospital, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-2254-6971
Chi Kong LiDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong.
Chinese University of Hong Kong · CNUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith advancements in the field of oncology, cancer survival rates have improved dramatically but modern cancer treatments also come with an increasing number of disease and treatment-associated complications. This article provides an updated narrative review on the pathophysiology, clinical presentations and latest management strategies for common paediatric oncological emergencies.

methodsAn extensive PubMed

resultsThe general description, presentation and management of these oncologic emergencies are systematically described. Early recognition along with prompt and proactive treatment can reduce the chances of potential complications and improve the clinical outcomes, thereby improving not only survival rates in oncology patients but also their clinical outcomes and quality of life.

conclusionsOncologic emergencies are associated with significant mortality and morbidity. Healthcare professionals involved with the care of oncology patients must be vigilant of these emergencies.

Indexed as

acute respiratory distress syndrome (ARDS)Cancercritical caredisseminated intravascular coagulationhyperleukocytosisoncologic emergencypaediatricsposterior reversible encephalopathy syndrome (PRES)sepsissuperior mediastinal syndrometherapeuticstreatmenttumour lysis syndrome

Identifiers

PMID34234831
PMCPMC8232653
OpenAlexW3176155549

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.