Evidence map›Paper›PMID 34234781›Full record

ArticleFrontiers in immunology2021

EGR3-HDAC6-IL-27 Axis Mediates Allergic Inflammation and Is Necessary for Tumorigenic Potential of Cancer Cells Enhanced by Allergic Inflammation-Promoted Cellular Interactions.

Yoojung Kwon, Misun Kim, Youngmi Kim, Myeong Seon Jeong, Hyun Suk Jung, Dooil Jeoung

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Mast cell-derived extracellular vesicles in lung diseases: roles in pulmonary inflammation, immune regulation, and microenvironmental remodeling.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  2. Article
  3. Article
  4. Crosstalk Between Allergic Inflammation and Autophagy.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Nur77 Mediates Anaphylaxis by Regulating miR-21a.Current issues in molecular biology · 2024
    Article
  9. EGR3 reduces podocyte inflammatory damage in obesity related glomerulopathy by inhibiting the PRMT1Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. The Role of Nuclear Factor-κB in Cancer Immunity and Immunoediting.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yoojung KwonDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Misun KimDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Youngmi KimInstitute of New Frontier Research, College of Medicine, Hallym University, Chuncheon, South Korea.
Myeong Seon JeongDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Hyun Suk JungDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.
Dooil JeoungDepartment of Biochemistry, Kangwon National University, Chuncheon, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to investigate mechanisms of allergic inflammation both

Indexed as

Cell CommunicationSignal TransductionAnimalsCell Line, TumorCell Transformation, NeoplasticCytokinesDisease SusceptibilityEarly Growth Response Protein 3FemaleHistone Deacetylase 6HypersensitivityInterleukin-27Melanoma, ExperimentalMiceMicroRNAsRatsCytokinesEarly Growth Response Protein 3Egr3 protein, mouseHistone Deacetylase 6Interleukin-27MicroRNAsallergic inflammationcellular interactionsEGR3HDAC6IL-27MiR-182-5p

Identifiers

PMID34234781
PMCPMC8257050

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.