Evidence map›Paper›PMID 34234694›Full record

ArticleFrontiers in physiology2021

TdP Incidence in Methoxamine-Sensitized Rabbit Model Is Reduced With Age but Not Influenced by Hypercholesterolemia.

Lukáš Nalos, Dagmar Jarkovská, Jitka Švíglerová, Annabell Süß, Jakub Záleský, Daniel Rajdl, Milada Krejčová, Jitka Kuncová, Josef Rosenberg, Milan Štengl

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In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lukáš NalosDepartment of Physiology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Dagmar JarkovskáDepartment of Physiology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Jitka ŠvíglerováDepartment of Physiology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Annabell SüßDepartment of Physiology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Jakub ZáleskýDepartment of Physiology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Daniel RajdlInstitute of Clinical Biochemistry and Haematology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Milada KrejčováNew Technologies for the Information Society, Faculty of Applied Sciences, University of West Bohemia, Pilsen, Czechia.
Jitka KuncováDepartment of Physiology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Josef RosenbergNew Technologies for the Information Society, Faculty of Applied Sciences, University of West Bohemia, Pilsen, Czechia.
Milan ŠtenglDepartment of Physiology, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.
Charles University · CZUniversity of West Bohemia · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome is associated with hypercholesterolemia, cardiac remodeling, and increased susceptibility to ventricular arrhythmias. Effects of diet-induced hypercholesterolemia on susceptibility to torsades de pointes arrhythmias (TdP) together with potential indicators of arrhythmic risk were investigated in three experimental groups of Carlsson's rabbit model: (1) young rabbits (YC, young control, age 12-16 weeks), older rabbits (AC, adult control, age 20-24 weeks), and older age-matched cholesterol-fed rabbits (CH, cholesterol, age 20-24 weeks). TdP was induced by α-adrenergic stimulation by methoxamine and I

Indexed as

amplitude-aware permutation entropyarrhythmia risk predictionhypercholesterolemiarabbitTdP arrhythmia

Identifiers

PMID34234694
PMCPMC8255784
OpenAlexW3174428241

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.