Evidence map›Paper›PMID 34234660›Full record

ArticleFrontiers in human neuroscience2021

Changes in Corticospinal Circuits During Premovement Facilitation in Physiological Conditions.

Giovanni Cirillo, Ilaria Antonella Di Vico, Mehran Emadi Andani, Francesca Morgante, Giovanna Sepe, Alessandro Tessitore, Matteo Bologna, Michele Tinazzi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Inhibition for gain modulation in the motor system.Experimental brain research · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Giovanni CirilloLaboratory of Morphology of Neuronal Network, Division of Human Anatomy, Department of Mental, Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Ilaria Antonella Di VicoMovement Disorders Division, Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Mehran Emadi AndaniMovement Disorders Division, Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Francesca MorganteNeurosciences Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London, United Kingdom.
Giovanna SepeLaboratory of Morphology of Neuronal Network, Division of Human Anatomy, Department of Mental, Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Alessandro TessitoreDivision of Neurology and Neurophysiopathology, Department of Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Matteo BolognaDepartment of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Michele TinazziMovement Disorders Division, Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Verona · ITSapienza University of Rome · ITSt George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in corticospinal excitability have been well documented in the preparatory period before movement, however, their mechanisms and physiological role have not been entirely elucidated. We aimed to investigate the functional changes of excitatory corticospinal circuits during a reaction time (RT) motor task (thumb abduction) in healthy subjects (HS). 26 HS received single pulse transcranial magnetic stimulation (TMS) over the primary motor cortex (M1). After a visual go signal, we calculated RT and delivered TMS at three intervals (50, 100, and 150 ms) within RT and before movement onset, recording motor evoked potentials (MEP) from the abductor pollicis brevis (APB) and the task-irrelevant abductor digiti minimi (ADM). We found that TMS increased MEP

Indexed as

MEPmotor cortexpremovement facilitationreaction timetranscranial magnetic stimulation

Identifiers

PMID34234660
PMCPMC8255790
OpenAlexW3174327819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.