Evidence map›Paper›PMID 34234630›Full record

ArticleInternational journal of health sciences

rs1445776009 variants in the human

Erick Barasa, Nathan Shaviya, Valentine Budambula, Tom Were

Open access · greenAbstract read
In one paragraph

Article in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Mechanistic Investigation of Curcuma Protection against Oral Submucous Fibrosis.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Erick BarasaDepartment of Medical Laboratory Sciences, Masinde Muliro University of Science and Technology, Kakamega, Kenya.
Nathan ShaviyaDepartment of Medical Laboratory Sciences, Masinde Muliro University of Science and Technology, Kakamega, Kenya.
Valentine BudambulaDepartment of Environment and Health Sciences, Technical University of Mombasa, Mombasa, Kenya, Mombasa, Kenya.
Tom WereDepartment of Medical Laboratory Sciences, Masinde Muliro University of Science and Technology, Kakamega, Kenya.
Masinde Muliro University of Science and Technology · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe coburden of human immunodeficiency virus (HIV) and injection substance use is high especially in coastal urban and peri-urban regions of sub-Saharan Africa. Although antiretroviral treatment (ART) has improved disease prognosis in HIV-1-infected patients, injection substance use is detrimental to these individuals. HIV-1 and injection substances use have been associated with a marked reduction in serum albumin levels. This is attributable to at least, in part, injection substance use, ARVs, HIV-1 infection, as well as host genetics. The albumin gene expression is modulated through several mechanisms including intronic consensus elements. Therefore, this study examined

methodsThis cross-sectional study was conducted at Bomu Hospital, Mombasa County, Kenya. A total of 155 injection substance users (ISUs) were recruited comprising 93 ART experienced and 62 ART naive. Variant rs1445776009 was amplified through polymerase chain reaction and genotyped through restriction fragment length polymorphism.

resultsCarriers of the mutant and GG had significantly lower body mass index (

conclusionThis study's findings appear to suggest that loci rs1445776009 of the

Indexed as

ALB geneantiretroviral treatmenthuman immunodeficiency virus-1injection substance userserum albumin

Identifiers

PMID34234630
PMCPMC8220640
OpenAlexW3165415912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.