Evidence map›Paper›PMID 34234605›Full record

ArticlePatient related outcome measures2021

Health-Related Quality of Life in Tuberculosis Patients in Eritrea: Comparison Among Drug-Susceptible and Rifampicin/Multidrug-Resistant Tuberculosis Patients.

Zenawi Zeramariam Araia, Araia Berhane Mesfin, Amanuel Hadgu Mebrahtu, Adiam Ghebreyohanns Tewelde, Asmerom Tesfagiorgis Tewelde, Solyana Ngusbrhan Kidane

Open access · goldAbstract read
In one paragraph

Article in Patient related outcome measures, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
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  5. The effects of stigma and social support on the health-related quality of life of people with drug resistance tuberculosis in Lagos, Nigeria.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  11. Health-related quality of life of persons living with tuberculosis: A cross-sectional study.Journal of clinical tuberculosis and other mycobacterial diseases · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zenawi Zeramariam AraiaNational TB and Leprosy Control Program, Communicable Disease Control Division, Ministry of Health, Asmara, Eritrea.ORCID 0000-0002-5756-438X
Araia Berhane MesfinCommunicable Diseases Control Division, Ministry of Health, Asmara, Eritrea.
Amanuel Hadgu MebrahtuNational TB and Leprosy Control Program, Communicable Disease Control Division, Ministry of Health, Asmara, Eritrea.
Adiam Ghebreyohanns TeweldeIntegrated Disease Surveillance and Response, Ministry of Health, Asmara, Eritrea.
Asmerom Tesfagiorgis TeweldeIntegrated Disease Surveillance and Response, Ministry of Health, Asmara, Eritrea.
Solyana Ngusbrhan KidaneHealth Systems, WHO Country Office for Eritrea, Asmara, Eritrea.
University of Asmara · ER

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundDespite the negative impact of tuberculosis (TB) on patients' quality of life, TB control programs focus on biological and clinical parameters to manage and monitor TB patients. In our setting, patients' perception of their experience with TB and the impacts of TB on patients' physical, mental, and social wellbeing remain unknown.

objectiveThe objective of this study was to evaluate the health-related quality of life (HRQOL) among rifampicin/multidrug-resistant TB (RR/MDR-TB) in comparison to drug-susceptible TB (DS-TB) patients in Eritrea.

methodsA cross-sectional study was conducted in RR/MDR-TB and DS-TB patients under treatment. Anonymized data collected using the WHOQOL-BREF questionnaire were analyzed using SPSS version 23. Frequency, mean and standard deviation were used to describe the data. Mean group score comparison and relationship between variables were assessed using

resultsA total of 92 patients (46 RR/MDR-TB and 46 DS-TB) participated in the study. Environmental (40.63 ± 10.72) and physical domains (61.80 ±17.18) were the two most affected domains in RR/MDR-TB and DS-TB patients, respectively. The psychological domain was the least affected domain in RR/MDR-TB (48.28 ± 20.83) and DS-TB patients (76.63 ±15.32). RR/MDR-TB patients had statistically lower mean scores in all domains than DS-TB patients.

conclusionHRQOL was impaired in both groups, but RR/MDR-TB patients had a worse health-related quality of life.

Indexed as

end TBmultidrug-resistant TBpatient-reported outcomequality of lifesub-Saharan Africa

Identifiers

PMID34234605
PMCPMC8254609
OpenAlexW3173769011

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.