Evidence map›Paper›PMID 34234550›Full record

ArticleCancer management and research2021

Value of Machine Learning with Multiphases CE-MRI Radiomics for Early Prediction of Pathological Complete Response to Neoadjuvant Therapy in HER2-Positive Invasive Breast Cancer.

Qin Li, Qin Xiao, Jianwei Li, Zhe Wang, He Wang, Yajia Gu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05068999 (Early Assessment of Shear Wave Elastography Parameters to Assess the Response to Neoadjuvant Chemotherapy in Patients With Invasive Breast Cancer), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05068999 unknown statusnot on this map

Early Assessment of Shear Wave Elastography Parameters to Assess the Response to Neoadjuvant Chemotherapy in Patients With Invasive Breast Cancer

TypeobservationalSponsorAssiut UniversityRan2021 to 2023Enrolled35ConditionsBreast NeoplasmsArmsshear wave elastography
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qin Li *Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Qin Xiao *Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.ORCID 0000-0002-5587-2928
Jianwei LiDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Zhe WangShanghai Center for Mathematical Sciences, Fudan University, Shanghai, People's Republic of China.
He WangShanghai Center for Mathematical Sciences, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-2053-9439
Yajia GuDepartment of Radiology, Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China.
Shanghai Medical College of Fudan University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the value of radiomics based on multiphases contrast-enhanced magnetic resonance imaging (CE-MRI) for early prediction of pathological complete response (pCR) to neoadjuvant therapy (NAT) in patients with human epithelial growth factor receptor 2 (HER2) positive invasive breast cancer.

methodsA total of 127 patients with newly diagnosed primary HER2 positive invasive breast cancer underwent CE-MRI before NAT and performed surgery after NAT. Radiomic features were extracted from the 1

resultsFor the task of pCR classification, 6 radiomic features from CE

conclusionMultiphases CE-MRI imaging may offer more heterogeneity information in the tumor and provide a non-invasive approach for early prediction of pCR to NAT in patients with HER2-positive invasive breast cancer.

Indexed as

breast cancermachine learningmagnetic resonance imagingneoadjuvant therapyradiomics

Identifiers

PMID34234550
PMCPMC8253937
OpenAlexW3173812093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.