Evidence map›Paper›PMID 34234520›Full record

ArticleInternational journal of general medicine2021

Prognostic Value of c-MYC Expression in Patients with Peripheral Neuroblastic Tumors.

Feng Zhang, Zhuo Tian, Tinghong Li, Xianjun Hu, Jin Zhu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. MYCN in Neuroblastoma: "Old Wine into New Wineskins".Diseases (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Feng ZhangDepartment of Otolaryngology, Children's Hospital of Chongqing Medical University, Chongqing, 400014, People's Republic of China.
Zhuo TianDepartment of Geratology, Chongqing General Hospital, Chongqing, 400014, People's Republic of China.
Tinghong LiDepartment of Pathology, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Xianjun HuDepartment of Geratology, Chongqing General Hospital, Chongqing, 400014, People's Republic of China.
Jin ZhuDepartment of Pathology, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Chongqing Medical University · CNFirst People's Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNeuroblastic tumors are the most common solid tumors in children. The aim of this study was to explore the prognostic value of immunostaining for cellular-myelocytomatosis viral oncogene (c-MYC) expression in patients with peripheral neuroblastic tumors (NTs).

methodsA retrospective study was conducted to compare the expression of c-MYC detected by immunohistochemistry and v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (

resultsThe cases positive for c-MYC were mainly the favorable histology type in stage 3 or 4 with a poor NT prognosis, but no morphological changes related to the poor prognosis were observed in their samples under a microscope. The cases with positive c-MYC expression did not overlap those with

conclusionPositive c-MYC expression portends a poor prognosis in patients with NTs.

Indexed as

c-MYCimmunostainingMYCNperipheral neuroblastic tumorsprognosis

Identifiers

PMID34234520
PMCPMC8254143
OpenAlexW3176391913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.