ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021
Foveal Avascular Zone Does Not Correspond to Choroidal Characteristics in Patients with Diabetic Retinopathy: A Single-Center Cross-Sectional Analysis.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 13 citations in OpenAlex.
- Linking cardiological parameters and choroidal changes in patients with precapillary pulmonary hypertension: a cross-sectional study.Scientific reports · 2025Article
- Macular choroidal thickness, volume, and vascularity index in patients with systemic sclerosis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Assessment of interocular symmetry of choroidal vascularity index and thickness in patients with systemic sclerosis: a prospective study.Frontiers in medicine · 2024Article
- Interocular Symmetry of Choroidal Parameters in Patients with Diabetic Retinopathy with and without Diabetic Macular Edema.Journal of clinical medicine · 2023Article
- Hyperbaric Oxygen Therapy in Ophthalmology: A Narrative Review.Journal of clinical medicine · 2023Review
- Peripapillary choroidal vascularity index and thickness in patients with systemic sclerosis.Frontiers in medicine · 2023Article
- Correlation between Choroidal Vascularity Index and Outer Retina in Patients with Diabetic Retinopathy.Journal of clinical medicine · 2022Article
- Diabetic macular ischaemia- a new therapeutic target?Progress in retinal and eye research · 2022Review
- Response to comment on "Intraocular fluid biomarkers (liquid biopsy) in human diabetic retinopathy." Graefes Arch Clin Exp Ophthalmol. 2021 Jul 3. doi: 10.1007/s00417-021-05285-y.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
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6 authors at 1 institution in 1 country.
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Abstract
purposeThe aim of the study was to compare two non-overlapping blood supply systems of the retina to obtain a better insight into the relation between diabetic macular retinopathy and choroidopathy. Specifically, the study focused on the relationships between (1) retinal vascular changes around the fovea in fluorescein angiography (FA) and (2) choroidal thickness, volume and other parameters assessed by optical coherence tomography (OCT). PATIENTS AND
methodsThe retrospective cross-sectional single-center study included 210 eyes from 152 patients with diabetic retinopathy (mean age 60.7±12.4 years, 49.3% of women; foveal avascular zone [FAZ] outline: 44.3% grade ≤2, 55.7% grade ≥3). The outline of FAZ, a measure of capillary loss due to ischemic processes, was analyzed on FA according to the Early Treatment Diabetic Retinopathy Study Research Group (ETDRS) standards. The eyes were stratified according to the FAZ outline and size and the presence of clinically significant diabetic macular edema (CSME). Then, resultant groups were compared in terms of the spectral domain OCT parameters: choroidal thickness and volume (within ETDRS subfields), luminal, stromal and total choroidal areas and choroidal vascularity index (based on the foveal scan). Statistical analysis was based on univariate models with the choroidal parameters as independent variables, and age, sex, panretinal photocoagulation, the severity of diabetic retinopathy and CSME as covariates.
resultsNo significant relationships were found between the FAZ outline and area and choroidal characteristics of patients with diabetic retinopathy. In patients without CSME, no correlation was observed between the FAZ area and choroidal characteristics. In patients with CSME, no correlation was found between the FAZ area and choroidal characteristics other than the choroidal vascularity index.
conclusionIn patients with diabetic retinopathy, damage to the macular retinal vasculature (FAZ) does not seem to be associated with changes in the choroidal vasculature, and these two processes appear to occur independently.
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