Evidence map›Paper›PMID 34234347›Full record

ArticleNature2021

A condensate-hardening drug blocks RSV replication in vivo.

Jennifer Risso-Ballester, Marie Galloux, Jingjing Cao, Ronan Le Goffic, Fortune Hontonnou, Aude Jobart-Malfait, Aurore Desquesnes, Svenja M Sake, Sibylle Haid, Miaomiao Du and 9 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed
24.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 225 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  20. How Oncovirus Affects Drug Resistance in Cancer Cells.Recent patents on anti-cancer drug discovery · 2026
    Review

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 5 countries.

Jennifer Risso-BallesterUniversité Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France.
Marie GallouxUnité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France.
Jingjing CaoHelmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China.
Ronan Le GofficUnité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France.ORCID http://orcid.org/0000-0002-2012-0064
Fortune HontonnouUnité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France.
Aude Jobart-MalfaitUniversité Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France.
Aurore DesquesnesUniversité Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France.
Svenja M SakeHelmholtz International Lab for Anti-Infectives, Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Sibylle HaidHelmholtz International Lab for Anti-Infectives, Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Miaomiao DuHelmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China.
Xiumei ZhangHelmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China.
Huanyun ZhangHelmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China.
Zhaoguo WangQingdao Municipal Center for Disease Control and Prevention, Qingdao, P. R. China.
Vincent RinchevalUniversité Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France.
Youming ZhangHelmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China.
Thomas PietschmannHelmholtz International Lab for Anti-Infectives, Institute for Experimental Virology, Twincore - Centre for Experimental and Clinical Infection Research, Hannover, Germany.ORCID http://orcid.org/0000-0001-6789-4422
Jean-François EléouëtUnité de Virologie et Immunologie Moléculaires (UR892), INRAE, Université Paris-Saclay, Jouy-en-Josas, France. jean-francois.eleouet@inrae.fr.ORCID http://orcid.org/0000-0002-7361-4885
Marie-Anne Rameix-Welti *Université Paris-Saclay, INSERM, Université de Versailles St Quentin, UMR 1173 (2I), Versailles, France. marie-anne.rameix-welti@uvsq.fr.ORCID http://orcid.org/0000-0002-5901-3856
Ralf Altmeyer *Helmholtz International Lab for Anti-Infectives, State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, Qingdao, P. R. China. ralf.marius.altmeyer@gmail.com.ORCID http://orcid.org/0000-0003-2794-459X
Shandong University · CNInserm · FRUniversité Paris-Saclay · FRCenter for Experimental and Clinical Infection Research · DEQingdao Municipal Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomolecular condensates have emerged as an important subcellular organizing principle

Indexed as

AnimalsAntiviral AgentsBiomolecular CondensatesCell LineFemaleHumansInclusion BodiesLungMiceMice, Inbred BALB CRespiratory Syncytial Virus, HumanRNA-Binding ProteinsTranscription FactorsVeratrum AlkaloidsViral ProteinsVirus ReplicationAntiviral Agentscyclopaminehuman respiratory syncytial virus M2-1 proteinRNA-Binding ProteinsTranscription FactorsVeratrum AlkaloidsViral Proteins

Identifiers

PMID34234347
OpenAlexW3179907723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.