Evidence map›Paper›PMID 34234054›Full record

ArticleThe Journal of veterinary medical science2021

Displaying epitope B and epitope 7 of porcine reproductive and respiratory syndrome virus on virus like particles of porcine circovirus type 2 provides partial protection to pigs.

Guopan Li, Lei Liu, Baojuan Xu, Jixiong Hu, Hongyan Kuang, Xi Wang, Liping Wang, Xiaoxia Cui, Houmin Sun, Jun Rong

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Guopan LiCollege of Life Science, Yangtze University, Jingzhou 434000, China.
Lei LiuState Key Laboratory of Animal Genetic Engineering Vaccine, Qingdao Yebio Biological Engineering Co., Ltd., Qingdao 266000, China.
Baojuan XuState Key Laboratory of Animal Genetic Engineering Vaccine, Qingdao Yebio Biological Engineering Co., Ltd., Qingdao 266000, China.
Jixiong HuCollege of Life Science, Yangtze University, Jingzhou 434000, China.
Hongyan KuangJingzhou Changxin Biotechnology Co., Ltd., Jingzhou 434000, China.
Xi WangJingzhou Changxin Biotechnology Co., Ltd., Jingzhou 434000, China.
Liping WangState Key Laboratory of Animal Genetic Engineering Vaccine, Qingdao Yebio Biological Engineering Co., Ltd., Qingdao 266000, China.
Xiaoxia CuiState Key Laboratory of Animal Genetic Engineering Vaccine, Qingdao Yebio Biological Engineering Co., Ltd., Qingdao 266000, China.
Houmin SunState Key Laboratory of Animal Genetic Engineering Vaccine, Qingdao Yebio Biological Engineering Co., Ltd., Qingdao 266000, China.
Jun RongCollege of Life Science, Yangtze University, Jingzhou 434000, China.
Yebio Bioengineering (China) · CNYangtze University · CNJingzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Cap of porcine circovirus type 2 (PCV2) can be assembled into virus like particles (VLPs) in vitro that have multiple loops located on the particle surface. This would make it a good vehicle for displaying exogenous proteins or epitopes. We derived two epitopes, epitope B (EpB, S

Indexed as

Circoviridae InfectionsCircovirusPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusViral VaccinesAnimalsAntibodies, ViralEpitopesSwineAntibodies, ViralEpitopesViral Vaccineschimeric porcine circovirus type 2 Capepitopehighly pathogenic porcine reproductive and respiratory syndrome virussurface displayvirus like particle

Identifiers

PMID34234054
PMCPMC8437722
OpenAlexW3180123103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.