Evidence map›Paper›PMID 34233999›Full record

ArticleBMJ open2021

Symptoms of common mental disorders and adherence to antiretroviral therapy among adults living with HIV in rural Zimbabwe: a cross-sectional study.

Andreas D Haas, Cordelia Kunzekwenyika, Stefanie Hossmann, Josphat Manzero, Janneke van Dijk, Ronald Manhibi, Ruth Verhey, Andreas Limacher, Per M von Groote, Ethel Manda and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03704805 (Effect of a Psychological Intervention on Antiretroviral Therapy Outcomes and Symptoms of Common Mental Disorders in HIV-positive Adults in Rural Zimbabwe), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03704805 nacompletednot on this map

Effect of a Psychological Intervention on Antiretroviral Therapy Outcomes and Symptoms of Common Mental Disorders in HIV-positive Adults in Rural Zimbabwe

TypeinterventionalSponsorUniversity of BernRan2018 to 2021Enrolled480ConditionsMental Disorder, HIV InfectionsArmsFriendship bench intervention, Enhanced Standard of Care
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 4 countries.

Andreas D HaasInstitute of Social & Preventive Medicine (ISPM), University of Bern, Bern, Switzerland andreas.haas@ispm.unibe.ch.ORCID 0000-0002-4849-181X
Cordelia KunzekwenyikaSolidarMed, Masvingo, Zimbabwe.
Stefanie HossmannInstitute of Social & Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Josphat ManzeroSolidarMed, Masvingo, Zimbabwe.
Janneke van DijkSolidarMed, Masvingo, Zimbabwe.
Ronald ManhibiSolidarMed, Masvingo, Zimbabwe.
Ruth VerheyFriendship Bench Zimbabwe, Harare, Zimbabwe.ORCID 0000-0002-5959-1891
Andreas LimacherCTU Bern, University of Bern, Bern, Switzerland.
Per M von GrooteInstitute of Social & Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
Ethel MandaFriendship Bench Zimbabwe, Harare, Zimbabwe.
Michael A HobbinsSolidarMed, Lucerne, Switzerland.
Dixon ChibandaFriendship Bench Zimbabwe, Harare, Zimbabwe.
Matthias EggerInstitute of Social & Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0001-7462-5132
IeDEA Southern Africa
University of Bern · CHUniversity of Zimbabwe · ZW

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

objectivesTo examine the proportion of people living with HIV who screen positive for common mental disorders (CMD) and the associations between CMD and self-reported adherence to antiretroviral therapy (ART).

settingSixteen government-funded health facilities in the rural Bikita district of Zimbabwe.

designCross-sectional study.

participantsHIV-positive non-pregnant adults, aged 18 years or older, who lived in Bikita district and had received ART for at least 6 months. OUTCOME MEASURES: The primary outcome was the proportion of participants screening positive for CMD defined as a Shona Symptoms Questionnaire score of 9 or greater. Secondary outcomes were the proportion of participants reporting suicidal ideation, perceptual symptoms and suboptimal ART adherence and adjusted prevalence ratios (aPR) for factors associated with CMD, suicidal ideation, perceptual symptoms and suboptimal ART adherence.

resultsOut of 3480 adults, 18.8% (95% CI 14.8% to 23.7%) screened positive for CMD, 2.7% (95% CI 1.5% to 4.7%) reported suicidal ideations, and 1.5% (95% CI 0.9% to 2.6%) reported perceptual symptoms. Positive CMD screens were more common in women (aPR 1.67, 95% CI 1.19 to 2.35) than in men and were more common in adults aged 40-49 years (aPR 1.47, 95% CI 1.16 to 1.85) or aged 50-59 years (aPR 1.51, 95% CI 1.05 to 2.17) than in those 60 years or older. Positive CMD screen was associated with suboptimal adherence (aPR 1.53; 95% CI 1.37 to 1.70).

conclusionsA substantial proportion of people living with HIV in rural Zimbabwe are affected by CMD. There is a need to integrate mental health services and HIV programmes in rural Zimbabwe. TRIAL REGISTRATION NUMBER: NCT03704805.

Indexed as

HIV InfectionsMental DisordersAdultCross-Sectional StudiesFemaleHumansMalePrevalenceRural PopulationZimbabweepidemiologyHIV & AIDSmental health

Identifiers

PMID34233999
PMCPMC8264908
OpenAlexW3178850402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.