ReviewBehavioral and brain functions : BBF2021
The mystery of claustral neural circuits and recent updates on its role in neurodegenerative pathology.
Review in Behavioral and brain functions : BBF, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Updated Intrinsic Role of Phytochemicals against Glyphosate-induced Neurotoxicity: Systematic Review.Current medicinal chemistry · 2025Pooled it
- Kappa opioids suppress histaminergic itch by inhibiting mediodorsal thalamus-projecting claustrum glutamatergic neurons.Science advances · 2026Article
- Brain-Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope-Tagged Knock-In Mouse.The Journal of comparative neurology · 2026Article
- Nurr1 Orchestrates Claustrum Development and Functionality.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The Human Claustrum Activates Across Multiple Cognitive Control Tasks.The European journal of neuroscience · 2025Article
- A Contrast-Agnostic Method for Ultra-High Resolution Claustrum Segmentation.Human brain mapping · 2025Article
- Brain-wide connectivity and novelty response of the dorsal endopiriform nucleus in mice.Cell reports · 2025Article
- Topic modeling analysis of the Allen Human Brain Atlas.Scientific reports · 2025Article
- The Role of the Claustrum in Parkinson's Disease and Vascular Parkinsonism: A Matter of Network?Life (Basel, Switzerland) · 2025Review
- Clinical and neuroimaging features of patients with claustrum sign.Frontiers in neurology · 2025Article
- The evolution of human-type consciousness - a by-product of mammalian innovation mechanism - a preliminary hypothesis.Frontiers in psychology · 2025Article
- Human Claustrum Connections: Robust In Vivo Detection by DWI-Based Tractography in Two Large Samples.Human brain mapping · 2024Article
- Clinical and neuroimaging features in neurological Wilson's disease with claustrum lesions.Scientific reports · 2024Article
- Localization of stuttering based on causal brain lesions.Brain : a journal of neurology · 2024Article
- Involvement of the claustrum in the cortico-basal ganglia circuitry: connectional study in the non-human primate.Brain structure & function · 2024Article
- The Constrained Disorder Principle May Account for Consciousness.Brain sciences · 2024Review
- The functional connectivity of the human claustrum, according to the Human Connectome Project database.PloS one · 2024Article
- Pathobiology of Cognitive Impairment in Parkinson Disease: Challenges and Outlooks.International journal of molecular sciences · 2023Review
- The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology.Nature communications · 2023Article
- The Claustrum Controls Motor Activity Through Anterior Cingulate Cortex Input and Local Circuit Synchronization in a Preparatory Manner.Neuroscience bulletin · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe claustrum is a structure involved in formation of several cortical and subcortical neural microcircuits which may be involved in such functions as conscious sensations and rewarding behavior. The claustrum is regarded as a multi-modal information processing network. Pathology of the claustrum is seen in certain neurological disorders. To date, there are not enough comprehensive studies that contain accurate information regarding involvement of the claustrum in development of neurological disorders.
objectiveOur review aims to provide an update on claustrum anatomy, ontogenesis, cytoarchitecture, neural networks and their functional relation to the incidence of neurological diseases. MATERIALS AND
methodsA literature review was conducted using the Google Scholar, PubMed, NCBI MedLine, and eLibrary databases.
resultsDespite new methods that have made it possible to study the claustrum at the molecular, genetic and epigenetic levels, its functions and connectivity are still poorly understood. The anatomical location, relatively uniform cytoarchitecture, and vast network of connections suggest a divergent role of the claustrum in integration and processing of input information and formation of coherent perceptions. Several studies have shown changes in the appearance, structure and volume of the claustrum in neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's disease (AD), autism, schizophrenia, and depressive disorders. Taking into account the structure, ontogenesis, and functions of the claustrum, this literature review offers insight into understanding the crucial role of this structure in brain function and behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.