Evidence map›Paper›PMID 34233589›Full record

ArticleVirulence2021

Pneumococcal surface adhesion A protein (PsaA) interacts with human Annexin A2 on airway epithelial cells.

Yoonsung Hu, Nogi Park, Keun Seok Seo, Joo Youn Park, Radha P Somarathne, Alicia K Olivier, Nicholas C Fitzkee, Justin A Thornton

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Human vaccines & immunotherapeutics · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Diverse Mechanisms of Protective Anti-Pneumococcal Antibodies.Frontiers in cellular and infection microbiology · 2022
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yoonsung HuDepartment of Biological Sciences, Mississippi State University, Mississippi State, USA.
Nogi ParkDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, USA.
Keun Seok SeoDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, USA.
Joo Youn ParkDepartment of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, USA.
Radha P SomarathneDepartment of Chemistry, Mississippi State University, Mississippi State, USA.
Alicia K OlivierDepartment of Population and Pathobiology, College of Veterinary Medicine, Mississippi State University, MS, USA.
Nicholas C FitzkeeDepartment of Chemistry, Mississippi State University, Mississippi State, USA.
Justin A ThorntonDepartment of Biological Sciences, Mississippi State University, Mississippi State, USA.ORCID 0000-0002-1191-8066
Mississippi State University · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
Zinc dependent conformational changes in AdcR and their impact on DNA bindingP20GM103646 · NIGMS · MISSISSIPPI STATE UNIVERSITY · PI NANDURI, BINDU · 2013 to 2022
$21.1M
Structure, Orientation, and Competitive Interactions of S. Epidermidis Biofilm Proteins on SurfacesR01AI139479 · NIAID · MISSISSIPPI STATE UNIVERSITY · PI FITZKEE, NICHOLAS C · 2018 to 2022
$1.8M
Rational design of an adhesin-based pneumococcal vaccine targeting colonizationR15AI142537 · NIAID · MISSISSIPPI STATE UNIVERSITY · PI THORNTON, JUSTIN A · 2020 to 2025
$946k
NIAID NIH HHS R01 AI139479NIAID NIH HHS R15 AI142537NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P20 GM103646
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Annexin A2Epithelial CellsStreptococcus pneumoniaeAdhesins, BacterialBacterial ProteinsCarrier ProteinsHEK293 CellsHumansLipoproteinsPneumococcal VaccinesAdhesins, BacterialAnnexin A2ANXA2 protein, humanBacterial ProteinsCarrier ProteinsLipoproteinsPneumococcal VaccinesPsaA protein, StreptococcusadhesionAnnexin A2 (Anxa2)colonizationhost cellular receptorprotein vaccineStreptococcus pneumoniaesurface protein adhesin A (PsaA)

Identifiers

PMID34233589
PMCPMC8274441
OpenAlexW3181312925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.