Evidence map›Paper›PMID 34233521›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2021

Association of genetic variants rs641153 (

Jamil M Neto, Marina Gm Viturino, Galina Ananina, Flávia F Bajano, Sueli M da S Costa, Alicia B Roque, Gessica Fs Borges, Raissa Franchi, Priscila Hh Rim, Flávio M Medina and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Immunogenetic and Environmental Factors in Age-Related Macular Disease.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jamil M NetoDepartment of Ophthalmology, Faculty of Medical Sciences - University of Campinas - Campinas, SP 13083-887, Brazil.ORCID 0000-0002-7024-1294
Marina Gm ViturinoDepartment of Ophthalmology, Faculty of Medical Sciences - University of Campinas - Campinas, SP 13083-887, Brazil.
Galina AnaninaLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering (CBMEG) - University of Campinas - Campinas, SP 13083-875, Brazil.
Flávia F BajanoLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering (CBMEG) - University of Campinas - Campinas, SP 13083-875, Brazil.
Sueli M da S CostaLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering (CBMEG) - University of Campinas - Campinas, SP 13083-875, Brazil.
Alicia B RoqueDepartment of Ophthalmology, Faculty of Medical Sciences - University of Campinas - Campinas, SP 13083-887, Brazil.
Gessica Fs BorgesDepartment of Ophthalmology, Faculty of Medical Sciences - University of Campinas - Campinas, SP 13083-887, Brazil.
Raissa FranchiLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering (CBMEG) - University of Campinas - Campinas, SP 13083-875, Brazil.
Priscila Hh RimDepartment of Ophthalmology, Faculty of Medical Sciences - University of Campinas - Campinas, SP 13083-887, Brazil.
Flávio M MedinaDepartment of Ophthalmology, Faculty of Medical Sciences, University of State of Rio de Janeiro - Rio de Janeiro, RJ 20551-030, Brazil.
Fernando F CostaHematology and Hemotherapy Center - University of Campinas - Campinas, SP 13083-878, Brazil.
Mônica B de MeloLaboratory of Human Genetics, Center for Molecular Biology and Genetic Engineering (CBMEG) - University of Campinas - Campinas, SP 13083-875, Brazil.ORCID 0000-0002-1801-5441
José Pc de VasconcellosDepartment of Ophthalmology, Faculty of Medical Sciences - University of Campinas - Campinas, SP 13083-887, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the association among genetic variants of the complement pathway

Indexed as

Polymorphism, Single NucleotideAgedAged, 80 and overBrazilCase-Control StudiesComplement C3Complement Factor BComplement Factor HFemaleGene FrequencyGenetic Predisposition to DiseaseGenotyping TechniquesHumansMacular DegenerationMaleMiddle AgedComplement C3Complement Factor BComplement Factor Hage-related macular degenerationComplement pathwaygenetic riskrs1410996rs2230199rs641153

Identifiers

PMID34233521
PMCPMC8581831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.