Evidence map›Paper›PMID 34233490›Full record

ArticleThe British journal of radiology2021

Evaluation of foot hypoperfusion and estimation of percutaneous transluminal angioplasty outcome in patients with critical limb ischemia using intravoxel incoherent motion microperfusion MRI.

Nikolaos Galanakis, Thomas G Maris, Georgios Kalaitzakis, Nikolaos Kontopodis, Nikolas Matthaiou, Stavros Charalambous, Konstantinos Tsetis, Christos V Ioannou, Apostolos Karantanas, Dimitrios Tsetis

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nikolaos GalanakisDepartment of Medical Imaging, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Thomas G MarisDepartment of Medical Physics, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Georgios KalaitzakisDepartment of Medical Physics, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Nikolaos KontopodisVascular Surgery Unit, Department of Cardiothoracic and Vascular Surgery, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Nikolas MatthaiouDepartment of Medical Imaging, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Stavros CharalambousDepartment of Medical Imaging, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Konstantinos TsetisDepartment of Medical Imaging, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Christos V IoannouVascular Surgery Unit, Department of Cardiothoracic and Vascular Surgery, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Apostolos KarantanasDepartment of Medical Imaging, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
Dimitrios TsetisDepartment of Medical Imaging, University Hospital Heraklion, University of Crete Medical School, Voutes, Heraklion, Greece.
University of Crete · GRUniversity Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo emerge hypoperfusion of lower limbs in patients with critical limb ischemia (CLI) using Intravoxel Incoherent Motion microperfusion magnetic resonance imaging (IVIM-MRI). Moreover to examine the ability of IVIM-MRI to differentiate patients with severe peripheral arterial disease (PAD) from normal subjects and evaluate the percutaneous transluminal angioplasty (PTA) results in patients with CLI.

methodsEight patients who presented with CLI and six healthy volunteers were examined. The patients underwent IVIM-MRI of lower extremity before and following PTA. The imaging protocol included sagittal diffusion-weighted (DW) sequences. DW images were analyzed and color parametric maps of the micro-circulation of blood inside the capillary network (D*) were constructed. The studies were evaluated by two observers to define interobserver reproducibility.

resultsTechnical success was achieved in all patients (8/8). The mean ankle-brachial index increased from 0.35 ± 0.2 to 0.76 ± 0.25 (

conclusionsIVIM-MRI can detect differences in microperfusion between patients with PAD and healthy individuals. Moreover, significant restitution of IVIM microperfusion is found following successful PTA. ADVANCES IN KNOWLEDGE: IVIM-MRI is a safe, reproducible and effective modality for evaluation of lower limb hypoperfusion in patients with PAD. It seems also to be a helpful tool to detect changes of tissue perfusion in patients with CLI following revascularization.

Indexed as

AdultAgedAngioplastyAnkle Brachial IndexFeasibility StudiesFemaleFootHumansIschemiaMagnetic Resonance ImagingMaleMiddle AgedPeripheral Arterial DiseaseProspective StudiesReproducibility of Results

Identifiers

PMID34233490
PMCPMC9327774
OpenAlexW3178835283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.