Evidence map›Paper›PMID 34233489›Full record

ArticleThe British journal of radiology2021

Chris W Govaerts, Bart Rj van Dijken, Gilles N Stormezand, Hiske L van der Weide, Michiel Wagemakers, Roelien H Enting, Anouk van der Hoorn

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Gut-to-tumor translocation of multidrug-resistantFrontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. [Scientific reports · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chris W GovaertsDepartment of Radiology (EB44), Medical Imaging Centre (MIC), University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Bart Rj van DijkenDepartment of Radiology (EB44), Medical Imaging Centre (MIC), University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Gilles N StormezandDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Centre (MIC), University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Hiske L van der WeideDepartment of Radiotherapy, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Michiel WagemakersDepartment of Neurosurgery, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Roelien H EntingDepartment of Neurology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Anouk van der HoornDepartment of Radiology (EB44), Medical Imaging Centre (MIC), University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
University Medical Center Groningen · NLUniversity of Cambridge · GBUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRadiation-induced changes (RIC) secondary to focal radiotherapy can imitate tumour progression in brain metastases and make follow-up clinical decision making unreliable.

methods26 patients with 31 metastatic lesions were included on the basis of having undergone a PET scan due to radiological uncertainty of disease progression. The PET images were analysed and methionine uptake quantified using standardised-uptake-values (SUV) and tumour-to-normal tissue (T/N) ratios, generated as SUV

resultsAll MET-PET parameters except metabolic-tumour-volume showed statistically significant differences between tumour progression and lesions with RIC. Receiver-operating-characteristic curve and area-under the-curve analysis demonstrated the highest value of 0.834 for SUV

conclusionsMET-PET is a useful modality for the diagnosis of RIC in brain metastases. SUV ADVANCES IN KNOWLEDGE: More robust comparisons between SUV

Indexed as

AgedBrainBrain NeoplasmsCarbon RadioisotopesCohort StudiesDiagnosis, DifferentialDisease ProgressionFemaleHumansMaleMethionineMiddle AgedPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsRetrospective StudiesCarbon RadioisotopesMethionineRadiopharmaceuticals

Identifiers

PMID34233489
PMCPMC9327750
OpenAlexW3178944167

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.