Evidence map›Paper›PMID 34233441›Full record

ArticleKidney research and clinical practice2021

Evolving outcomes of peritoneal dialysis: secular trends at a single large center over three decades.

Minjung Kang, Yae Lim Kim, Eunjeong Kang, Hyunjin Ryu, Yong Chul Kim, Dong Ki Kim, Hajeong Lee, Seung Seok Han, Kwon-Wook Joo, Yon Su Kim and 2 more

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In one paragraph

Article in Kidney research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Minjung KangDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Yae Lim KimDepartment of Biostatistics, Korea University College of Medicine, Seoul, Republic of Korea.
Eunjeong KangDepartment of Internal Medicine, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Hyunjin RyuDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Yong Chul KimDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Dong Ki KimDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Hajeong LeeDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Seung Seok HanDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Kwon-Wook JooDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Yon Su KimDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Curie AhnDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Kook-Hwan OhDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Funding

Fresenius Medical Care, Korea 06-2016-1040
6 · The paper itself

Abstract

backgroundPeritoneal dialysis (PD) is improving as a renal replacement therapy for end-stage renal disease (ESRD) patients. We analyzed the main outcomes of PD over the last three decades at a single large-scale PD center with an established high-quality care system.

methodsAs a retrospective cohort study, we included participants (n = 1,203) who began PD between 1990 and 2019. Major PD-related outcomes were compared among the three 10-year cohorts.

resultsThe 1,203 participants were 58.3% male with a mean age of 47.9 ± 13.8 years. The median PD treatment duration was 45 months (interquartile range, 19-77 months); 362 patients (30.1%) transferred to hemodialysis, 289 (24.0%) received kidney transplants, and 224 (18.6%) died. Overall, the 5- and 8-year adjust patient survival rates were 64% and 49%, respectively. Common causes of death included infection (n = 55), cardiac (n = 38), and cerebrovascular (n = 17) events. The 5- and 8-year technique survival rates were 77% and 62%, respectively, with common causes of technique failure being infection (42.3%) and solute/water clearance problems (22.7%). The 5-year patient survival significantly improved over time (64% for the 1990-1999 cohort vs. 93% for the 2010-2019 cohort). The peritonitis rate also substantially decreased over time, from 0.278 episodes/patient-year (2000-2004) to 0.162 episodes/patient-year (2015-2019).

conclusionPD is an effective treatment option for ESRD patients. There was a substantial improvement in the patient survival and peritonitis rates over time. Establishing adequate infrastructure and an effective system for high-quality PD therapy may be warranted to improve PD outcomes.

Indexed as

Peritoneal dialysisPeritonitisSurvivalTechnique failure

Identifiers

PMID34233441
PMCPMC8476299

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.