ArticleKidney research and clinical practice2021
Mortality predictors in critically ill patients with acute kidney injury requiring continuous renal replacement therapy.
Article in Kidney research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Volume control strategy and patient survival in sepsis-associated acute kidney injury receiving continuous renal replacement therapy: a randomized controlled trial with secondary analysis.Scientific reports · 2024Trial
- Four-organ SOFA score as a potential tool to triage use of continuous kidney replacement therapy in COVID-19 patients with acute kidney injury: a retrospective two-center study.Renal failure · 2026Article
- Article
- Acute kidney injury and COVID-19: the predictive power of BUN/albumin ratio for renal replacement therapy requirement.Irish journal of medical science · 2024Article
- Cystatin C and Kidney Function Recovery in Patients Requiring Continuous KRT for Acute Kidney Injury.Clinical journal of the American Society of Nephrology : CJASN · 2024Article
- Plasma presepsin for mortality prediction in patients with sepsis-associated acute kidney injury requiring continuous kidney replacement therapy.Kidney research and clinical practice · 2024Article
- Clinical Profile and Short-Term Outcomes of Acute Kidney Injury in Elderly Patients in a Tertiary Care Center.Cureus · 2024Article
- Mortality Rate and Its Contributing Factors in Post-Surgical and Medical Patients with AKI Underwent CRRT.Tanaffos · 2024Article
- Diagnostic and Prognostic Roles of C-Reactive Protein, Procalcitonin, and Presepsin in Acute Kidney Injury Patients Initiating Continuous Renal Replacement Therapy.Diagnostics (Basel, Switzerland) · 2023Article
- Development and validation of prediction model using nursing notes on sentiment scores for prognosis of patients with severe acute kidney injury receiving continuous renal replacement therapy based on computational intelligence algorithms.Annals of translational medicine · 2022Article
- Role of bicarbonate and volume therapy in the prevention of acute kidney injury in rhabdomyolysis: a retrospective propensity score-matched cohort study.Kidney research and clinical practice · 2022Article
- Overview of Renal Replacement Therapy Use in a General Intensive Care Unit.International journal of environmental research and public health · 2022Observational
- Article
- Continuous Renal Replacement Therapy for Hypertension Complicated by Refractory Heart Failure: An Analysis of Safety and Nursing Highlights.Computational and mathematical methods in medicine · 2022Article
- Predictors of Mortality in Adults with Acute Kidney Injury Requiring Dialysis: A Cohort Analysis.International journal of nephrology · 2022Article
- Association of Serum Phosphate Derangement With Mortality in Patients on Continuous Renal Replacement Therapy.Canadian journal of kidney health and disease · 2022Article
- Continuous Renal Replacement Therapy: Application of Kidney Disease Improving Global Outcomes Guidelines for Treatment Prescription in Dogs With Acute Kidney Injury and Outcome Prediction.Journal of veterinary internal medicineArticle
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Authors and funding
8 authors.
Funding
Abstract
backgroundBecause of high cost of continuous renal replacement therapy (CRRT) and the high mortality rate among severe acute kidney injury patients, careful identification of patients who will benefit from CRRT is warranted. This study determined factors associated with mortality among critically ill patients requiring CRRT.
methodsThis was a retrospective observational study of 414 patients admitted to the intensive care unit of four hospitals in South Korea who received CRRT from June 2017 to September 2018. Patients were divided according to degree of fluid overload (FO) and disease severity. The Cox proportional hazards model was used to explore the effect of relevant variables on mortality.
resultsIn-hospital mortality rate was 57.2%. Ninety-day mortality rate was 58.5%. Lower creatinine and blood pH were significant predictors of mortality. A one-unit increase in the Sequential Organ Failure Assessment (SOFA) score was associated with increased risk of and 90-day mortality (hazard ratio [HR], 1.07; p < 0.001). The risk of 90-day mortality in FO patients was 57.2% (p < 0.001) higher than in those without FO. High SOFA score was associated with increased risk for 90-day mortality (HR, 1.79; p = 0.03 and HR, 3.05; p = 0.001) in patients without FO and with FO ≤ 10%, respectively. The highest mortality rates were in patients with FO > 10%, independent of disease severity.
conclusionFO increases the risk of mortality independent of other factors, including severity of acute illness. Prevention of FO should be a priority, especially when managing the critically ill.
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