Evidence map›Paper›PMID 34233043›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand.

Ana L Aguirre, Nathan L Loud, Keywan A Johnson, Daniel J Weix, Ying Wang

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
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  7. Article
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  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Formal Cross-Coupling of Amines and Carboxylic Acids to Form spJournal of the American Chemical Society · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana L AguirreAdvanced Chemistry Technologies Group, AbbVie, 1 N Waukegan Road, North Chicago, IL 60064, USA.ORCID http://orcid.org/0000-0002-4953-6768
Nathan L LoudDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Ave, Madison, WI 53706, USA.ORCID http://orcid.org/0000-0002-1764-5732
Keywan A JohnsonDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Ave, Madison, WI 53706, USA.ORCID http://orcid.org/0000-0001-8021-185X
Daniel J WeixDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Ave, Madison, WI 53706, USA.ORCID http://orcid.org/0000-0002-9552-3378
Ying WangAdvanced Chemistry Technologies Group, AbbVie, 1 N Waukegan Road, North Chicago, IL 60064, USA.ORCID http://orcid.org/0000-0001-9516-3483

Funding

Reductive Coupling Reactions: Trading Organometallic Reagents for Organic HalidesR01GM097243 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Daniel John Weix · 2011 to 2026
$5.6M
AbbVie BiotherapeuticsNIGMS NIH HHS R01 GM097243NIGMS NIH HHS R01GM097243
6 · The paper itself

Abstract

High-throughput experimentation (HTE) methods are central to modern medicinal chemistry. While many HTE approaches to C-N and Csp

Indexed as

Heterocyclic CompoundsNickelBromidesCatalysisLigandsBromidesHeterocyclic CompoundsLigandsNickelcarbon-carbon bond formationcross-electrophile couplinghigh-throughput experimentationmedicinal chemistrynickel

Identifiers

PMID34233043
PMCPMC8554800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.