Evidence map›Paper›PMID 34232912›Full record

ArticleThe American journal of tropical medicine and hygiene2021

Mortality in Parenchymal and Subarachnoid Neurocysticercosis.

Jesus Abanto, Daniel Blanco, Herbert Saavedra, Isidro Gonzales, Diego Siu, E Javier Pretell, Javier A Bustos, Hector H Garcia, Cysticercosis Working Group in Peru

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Photo Quiz: No brainer-hydrocephalus in a 39-year-old male.Journal of clinical microbiology · 2026
    Article
  2. Three decades of neurocysticercosis mandatory notification in a Brazilian endemic region: clinical evolution and severity patterns.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Repair capacity ofFuture microbiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Older Age in Subarachnoid Neurocysticercosis Reflects a Long Prepatent Period.The American journal of tropical medicine and hygiene · 2023
    Article
  17. Article
  18. A Rapid Point-of-Care Assay for Cysticercosis Antigen Detection in Urine Samples.The American journal of tropical medicine and hygiene · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jesus Abanto1Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Peru.
Daniel Blanco3Unidad de Investigación, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Herbert Saavedra2Centro Básico de Investigación en Exámenes Auxiliares en Parasitosis Del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Isidro Gonzales2Centro Básico de Investigación en Exámenes Auxiliares en Parasitosis Del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Diego Siu1Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Peru.
E Javier Pretell4Hospital Nacional Alberto Sabogal, Essalud, Callao, Peru.
Javier A Bustos1Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Peru.
Hector H Garcia1Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Peru.
Cysticercosis Working Group in Peru
Instituto Nacional de Ciencias NeurológicasInstituto Nacional de Enfermedades Neoplásicas · PENational University of Callao · PEUniversidad Peruana Cayetano Heredia · PE

Funding

Training in Parasitic Diseases and Central Nervous System Infections in Peru.D43TW001140 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI GARCIA, HECTOR HUGO, GILMAN, ROBERT H · 1999 to 2025
$5.7M
FIC NIH HHS D43 TW001140
6 · The paper itself

Abstract

Neurocysticercosis (NCC) is endemic in many parts of the world, carrying significant neurological morbidity that varies according to whether lesions are located inside the cerebral parenchyma or in extraparenchymal spaces. The latter, in particular subarachnoid NCC, is assumed to be more severe, but no controlled studies comparing mortality between types of NCC exist. The aim of this study was to compare all-cause mortality between patients with intraparenchymal NCC and those with subarachnoid NCC. Vital status and sociodemographic characteristics were evaluated in patients with intraparenchymal viable, intraparenchymal calcified, and subarachnoid NCC attending a neurological referral hospital in Lima, Perú. Survival analyses using Kaplan-Meier curves and Cox proportional regression models were carried out to compare mortality rates between groups. From 840 NCC patients followed by a median time of 82.3 months, 42 (5.0%) died, six (1.8%) in the intraparenchymal viable group, four (1.3%) in the calcified group, and 32 (16.6%) in the subarachnoid group (P < 0.001). Older age and lower education were significantly associated with mortality. The age-adjusted hazard ratio for death in the subarachnoid group was 13.6 (95% CI: 5.6-33.0, P < 0.001) compared with the intraparenchymal viable group and 10.7 (95% CI: 3.7-30.8, P < 0.001) when compared with the calcified group. We concluded that subarachnoid disease is associated with a much higher mortality in NCC.

Indexed as

AdultAnimalsFemaleHumansMaleMiddle AgedNeurocysticercosisSubarachnoid SpaceTaenia solium

Identifiers

PMID34232912
PMCPMC8274779
OpenAlexW3179146616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.